Protein microcapsules (PM) were developed as a tool for investigating aspects of dietary protein utilization by mussels, Mytilus edulis trossulus. Digestion of PM in vitro by protease, trypsin, amylase and extracts from the gut of mussels varied significantly depending on the type of protein encapsulated or whether carbohydrates were added...
A crucial factor in determining the accuracy of DNA replication is
maintenance of a balanced supply of deoxyribonucleoside triphosphates
(dNTPs) at replication forks. Perturbation of dNTP biosynthesis can
induce dNTP pool imbalance with deleterious genetic consequences,
including increased mutagenesis, recombination, chromosomal
abnormalities and cell death. Using the T4 bacteriophage system,...
The acute phase response (APR) includes an early response of the innate immune
system to an inflammatory agent. Acute phase proteins (APP) are produced at
increased rates in the liver during this response. The APR has been well
characterized in mammals, but it is unclear to what degree teleosts mount...
The first committed step in DNA biosynthesis occurs by direct reduction of
ribonucleotides. This reduction is catalyzed by ribonucleotide reductase (RNR), an
enzyme which uses a unique radical mechanism to facilitate the transformation. All four
DNA precursors are synthesized by a single enzyme. Therefore, an intricate pattern of
regulation has...
Devaleraea mollis (Pacific Dulse) is becoming a popular food for human consumption. Previously, Pacific Dulse has been used as a nutrient source for cultured abalone species, with some historical food use by indigenous peoples, while the closely related Atlantic dulse (Palmaria palmata) has a long-documented history of use in cuisine...
Large numbers of reinforced concrete deck girder bridges that were constructed during the
interstate system expansion of the 1950s have developed diagonal cracking in the stems.
Compared to the present AASHTO-LRFD standards, the provisions of the 1950s allowed
for higher shear stress in the concrete, thus reducing the amount of...
Vibrio coralliilyticus (Vcor) is a bacterial pathogen that is well adapted to shellfish hatcheries and is very pathogenic to the larvae of the Pacific oyster Crassostrea gigas. Vcor has been associated with several large scale larval mortality events in the Pacific Northwest that interrupt the supply of seed oysters available...
A 1 kW series hybrid powertrain was developed at Oregon State University for use in unmanned aerial vehicles (UAVs). This powertrain was designed to give mission flexibility and increased flight time to fixed-wing vertical takeoff and landing UAVs and multirotor UAVs. The powertrain components, an internal combustion engine and a...
This dissertation describes an investigation of DNA precursor supply for mitochondrial and nuclear DNA synthesis in HeLa cells and Mouse L-cells. HeLa cells were used for the quantitation of cellular and mitochondrial deoxyribonucleoside triphosphate (dNTP) and ribonucleoside triphosphate (rNTP) pools and of changes in pools in response to treatment with...