Background/Objectives: Advanced glycation end products (AGEs) are implicated in the pathogenesis of atherosclerosis, diabetes and kidney disease. The objective was to describe dietary intake, the dominant source of exposure to AGEs, with carboxymethyl-lysine (CML), a major AGE, in serum and urine, respectively.
Subjects/Methods: Serum and urinary CML were measured in...
Pre-spawning mortality (PSM) presents a major problem for population recovery of spring Chinook salmon (Oncorhynchus tshawytscha) in the Willamette River basin. In certain reaches and years, PSM has exceeded 90%. Histology has been used as the primary diagnostic method to investigate PSM in the Chinook Salmon, and a collection of...
The purpose of this study was to determine if a 5-month
progressive-resistance exercise program would affect measures
of activities of daily living (ADLs) and functional stability
in elderly women. All subjects were ambulatory women, 80 to
93 years old, who lived in assisted-care facilities. Eight
exercise and 7 control subjects...
The purpose of this study was to determine if feeding dogs medium-chain triglycerides (MCT), fish oil, and L-carnitine enriched foods offsets age-associated changes in serum fatty acids (FA) and carnitine metabolites. Forty-one healthy Beagles, mean age 9.9 years (range 3.1 to 14.8), were fed control or one of two treatment...
Low physical activity levels and high serum C-reactive protein (CRP) levels are risk factors for coronary artery disease (CAD) in both men and women. However, postmenopausal women who take hormone replacement therapy (HRT) may have increased risk of CAD because of HRT-related increases in serum CRP. There are two manuscripts...
Health officials have recently been sounding the alarm that depression will soon
surpass many of the major medical conditions in causing disability among adults. Recent
demographic and health trends are generating public health concern about depression.
First, the prevalence of chronic conditions has dramatically increased over the last several
generations....
Case control studies of nonagenarians and centenarians provide evidence that long‐lived individuals do not
differ in the rate of disease associated variants compared to population controls. These results suggest that an enrichment
of novel protective variants, rather than a lack of disease associated variants, determine the genetic predisposition to
exceptionally...
Full Text:
, Andersen SL, Daw EW,
Terracciano A, FerrucciL and Perls TT. Genome‐wide association
study of
Purpose: We examined the prevalence and correlates of unmet assistance need with respect to activities of daily living (ADLs) and instrumental activities of daily living (IADLs) among older American Indians.
Design and Methods: Data for our analyses were collected in 2006–2008 as part of the Native Elder Care Study, a...
This study explores how a platform enables social media influencers to promulgate a consumption ideology. We show how gun influencers, or “gunfluencers,” use Instagram to link products, activities, and meanings to Second Amendment ideology—a gun-centric belief system in the United States colloquially known as “2A ideology.” Through a qualitative study...
The pursuit of personal goals has been linked to general psychological well-being, however, less is known about the association with depression in later adulthood when individuals are contending with age-related changes in health and social relationships. We explored the connection between both health and social relation goals (as measured by...