Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing
trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor
prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc
orthologs, myca and mycb, it remains unclear about the oncogenicity of...
Full Text:
in tp53 Null Mutation
Lili Sun1, AnhTuan Nguyen1¤, Jan M. Spitsbergen2, Zhiyuan Gong1*
1Department
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent immunosuppressant, and suppresses many disease models including graft-versus-host (GVH), experimental autoimmune encephalomyelitis (EAE) and a model of type 1 diabetes in non-obese diabetic (NOD) mice (1-3). In this study, we show that the inflammation of the pancreas due to insulitis is not a systemic autoimmune...
Full Text:
insulitis in NOD
mice
Tuan Pham
Dr. Nancy Kerkvliet
Environmental and Molecular Toxicology
Oregon State
Here we report a new transgenic expression system by combination of liver-specific expression,
mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic
kras[superscript]V12. This transgenic system allowed expression of kras[superscript]V12 specifically in the liver by a brief exposure
of mifepristone to induce permanent genomic recombination mediated by...
Full Text:
expression in transgenic zebrafish
AnhTuan Nguyen
1, 2
, Vivien Koh
1
, Jan M. Spitsbergen
2
Here we report a new transgenic expression system by combination of liver-specific expression,
mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic
kras[superscript]V12. This transgenic system allowed expression of kras[superscript]V12 specifically in the liver by a brief exposure
of mifepristone to induce permanent genomic recombination mediated by...
Full Text:
control oncogenic krasV12
expression in transgenic zebrafish
AnhTuan Nguyen1,2, Vivien Koh1, Jan M
Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing
trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor
prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc
orthologs, myca and mycb, it remains unclear about the oncogenicity of...
For many years, researchers have used the theory of planned behaviour (TPB) in order to suggest that human behaviour is greatly influenced by people’s preferences and attitudes, social norms, perceived behavioural control and intentions to act (Ajzen, 1991; Armitage and Conner, 2001) [1], [2]. Over the last 20 years, this...
Full Text:
BEHAVIOUR
Le Chi Cong, University of Nhatrang, Vietnam, lechicongntu@yahoo.com
Abstract
This study
The paper adopts the double-bootstrap data envelopment analysis developed by Simar and Wilson in 2007 to estimate and explain technical efficiency of white-leg shrimp farming in Ninh Thuan, Vietnam. This procedure not only enables consistent inference within models explaining efficiency scores but also produces confidence intervals for these efficiency scores....
Full Text:
application of the double-bootstrap data envelopment analysis
LE, VAN THAP
The Faculty of Economics
The northern part of the Southeast Three Sisters quadrangle straddles
the crest of the central High Cascades of Oregon. The area is
covered by Pleistocene and Holocene volcanic and volcaniclastic rocks
that were extruded from a number of composite cones, shield volcanoes,
and cinder cones. The principal eruptive centers include...
Full Text:
andesite lavas
and cinders were extruded from the Le Conte vent at the southwest base
of South Sister
The Ataspaca prospect is in the Cordillera Occidental, 45 km northwest of Tacna, Peru. Epizonal intrusions satellitic to the Caplina- Ataspaca pluton were emplaced 41 m.y. ago into limestones of the Lower Jurassic Pelado Formation along the northeast-trending Chucchuco fault system. Depths of emplacement ranged from 4.5 to 6.0 km....