Small chemicals like drugs tend to bind to proteins via noncovalent bonds, e.g. hydrogen bonds, salt bridges or electrostatic interactions. Some chemicals interact with other molecules than the actual target ligand, representing so-called ‘off-target' activities of drugs. Such interactions are a main cause of adverse side effects to drugs and...
The overall objective of the research reported here is to
empirically measure the ability of farmers to mitigate the impact of
rising electricity prices by substituting relatively inexpensive
alternative inputs. A dual cost methodology is employed because it
allows theoretically consistent derivation of own price and factor
substitution elasticities, conditional...
A fully integrated CMOS GPS receiver RF front end optimized for low power operation is presented. The system operates with a supply voltage down to 250 mV. A prototype has been fabricated in a 0.13μm CMOS process and includes a low voltage LNA, quadrature oscillators, and quadrature mixers. It exhibits...
The conservation of open space will become increasingly important as populations expand and undeveloped land is converted to urban uses. The benefits derived from open space conservation include protecting and improving water quality, providing wildlife habitat, maintaining scenic amenities and rural character, and supplying certain recreational opportunities. This study utilizes...
Focus is published by Oregon State University's College of Forestry. Our goal is to keep Forestry alumni, friends, faculty, staff, and students informed about the College of Forestry and its many activities and programs.
Coastal stream basins are of great importance to efforts aimed at refining our understanding of the earliest populations that inhabited the ancient Oregon coast. However, geomorphic responses to post-glacial sea level rise in these settings has produced depositional environments that destroy or deeply bury late Pleistocene and early Holocene-age archaeological...
Back pain is the leading cause of disability worldwide, entailing a significant socioeconomic impact. A primary source of back pain can be attributed to intervertebral disc (IVD) degeneration allowing nerve ingrowth, facet joint arthritis, disc bulging, and osteophyte formations that press on nearby nerve roots or the spinal cord. While...
Racial, ethnic and gender diversity have been long term topics of discussion in natural resources. Yet to date, there has not been a comprehensive review of the existing literature within the discourse of demographic diversity. Therefore, I conducted a systematic review of demographic diversity in the disciplines of forestry, fisheries,...
Non-structural carbohydrates (NSC) in plant tissue are frequently quantified to make inferences about plant responses to environmental conditions. Laboratories publishing estimates of NSC of woody plants use many different methods to evaluate NSC. We asked whether NSC estimates in the recent literature could be quantitatively compared among studies. We also...
I am a woman who writes. I am a writer who is a woman. In the Words
of a Woman is an exploration of how these two facts of my life merge and
influence each other. It is a work written to mediate between the supposed
dichotomies of creative and...
We describe a series of novel computational models, CERENKOV (Computational Elucidation of the REgulatory NonKOding Variome) and its successors CERENKOV2, CERENKOV3, and Convolutional CERENKOV3, for discriminating regulatory single nucleotide polymorphisms (rSNPs) from non-regulatory SNPs within non-coding genetic loci. The CERENKOV models are designed for recognizing rSNPs in the context of...
It is well documented that microplastics and semi-synthetic particles (<5 mm) pervade the marine environment, with their ingestion by marine fauna eliciting global concern. While fishes exposed to microparticles in a laboratory setting have exhibited both sub-lethal and lethal effects, the diversity in material, morphology, and size of these contaminants...
This dissertation focuses on personal privacy in human-robot interaction, which we call "privacy-sensitive robotics." Our understanding of "privacy" is very broad, including not just information privacy but also physical, psychological, and social privacy. We begin by surveying the scholarly literature on privacy and talking about why it applies to interactions...
After contamination of soil in Japan due to the Fukushima Daiichi accident, there has been an increased interest in remediation of radiologically contaminated land. This study investigated the efficacy of a new biological remediation technology developed by Earthfort, an Oregon based company to hold radionuclides at the soil surface. Cesium-134...
The social sciences have the capacity to contribute to natural resource management through investigations of human dynamics associated with the environment. Sense of place (SOP), the formed relationships between an individual and the environment, has been considered a fundamental aspect of human well-being and can contribute to more holistic understanding...
This thesis is based on a two-part study that analyzes the cultural and linguistic characteristics of the Hawaii student population at Oregon State University (OSU). I designed and conducted a survey among Hawaii students at OSU. Then I interviewed ten Hawaii students who self-identified as Hawaii Creole English (a.k.a. Pidgin)...
The purpose of this study is to illuminate the presence
and rhetorical effect of anecdotes in President Clinton's
major health care address. It is the health care debate that
shows most clearly how Clinton tries to direct a multi-level
campaign that attempts to identify his interests (passage of
the Health...
There is an urgent need to lower the concentration of sulfur in diesel fuels. Growing concern over environmental effects caused by burning sulfur-containing diesel has led the world to higher standards in fuel refinement. Because of these lower standards, many techniques have been researched to remove sulfur containing compounds or...
While much has been written about why people join social movements in general, little has been written about why people specifically join either militant or nonviolent social movements. Using the Black Panther Party as an example of a militant social movement and the mainstream Civil Rights Movement as an example...
"What’s wrong with this AI?" Explainable AI (XAI) researchers are moving beyond explaining an AI’s actions, to helping users detect an AI’s failures. However this detection may not be enough—for actionability, we often need to pinpoint which part failed. We investigate how AAR/AI, a structured assessment process, supports users with...
Limnology is undergoing a transition to high-throughput -omic analysis of freshwater
bacterial communities. An important first step in making the transition is to
characterize several genomes that can be used as references to guide metagenome
assembly and analysis. Here I characterize four new freshwater cyanobacterial
genomes, a pair of lake...
Diversity literary awards and other sources were used to create a list of high-quality titles written by and about underrepresented groups. This list was used to assess the diversity and inclusiveness of the library collections of a land-grant university. Gaps in the collection and acquisition processes were identified and will...
Vessel traffic places the sensitive environmental, natural, and cultural resources of Washington’s outer coast at risk of oil or hazardous materials spills. In 1995, International Maritime Organization established the Area to be Avoided off the Washington Coast (ATBA) to reduce this risk. Annual estimates of vessel compliance with the ATBA...
The purpose of the study was to determine the nature and
extent of furniture in use in the fourteenth and fifteenth centuries in
England, France, and the Low Countries (Holland, Belgium, and
Northwest France) as portrayed in illuminated manuscripts of that
period.
Reproduced copies of illuminated manuscripts and books containing...
This thesis will cover work that I have completed relating to the field of terahertz (THz) science. My work has consisted of generating tunable, narrowband THz pulses in a table-top optical setup and using both narrow- and broadband THz pulses to study various material systems. Broadband THz pulses were used...
Generally presented as a preferred social norm based on both ethical considerations and legislative demands, gender equality has been highly encouraged in recent years. For instance, The United Nations Sustainable Development Goals for 2030 call out achieving gender equality and empowerment of women. However, although there are multiple efforts to...
Emerging research shows that individual differences in how people use technology sometimes cluster by socioeconomic status (SES) and that when technology is not socioeconomically inclusive, low-SES individuals may abandon it. To understand how to improve technology’s SES-inclusivity, we present a multi-phase case study on SocioEconomicMag (SESMag), an emerging inspection method...
Climate change and efforts to address it have put the electric utility system under increasing pressure to adapt and evolve. Key to the success of these efforts will be the support of public utility commissions, the state agencies that oversee retail electric utilities. In an effort to determine how these...
Organic semiconductors have attracted considerable attention due to their applications in low-cost, solution-processable (opto)electronic devices. An important class of high-performance organic semiconductors is pentacene derivatives, which exhibit high charger carrier mobilities in field-effect transistors and ultrafast singlet fission in photovoltaic devices. These derivatives have served as benchmark materials for systematic...
There has been a growing interest in eating disorders among Singaporean medical professionals since the 1990s, and the Singaporean public is also starting to become aware of the risks of these conditions. This ethnographic research on eating disorders in Singapore, conducted in 2001, however, found that the majority of the...
Within the past several years the technology of high-throughput sequencing has transformed the study of biology by offering unprecedented access to life's fundamental building block, DNA. With this transformation's potential a host of brand-new challenges have emerged, many of which lend themselves to being solved through computational methods. From de...
This thesis is an offering, request, testimonio, refusal, and compliance to the discipline of anthropology and higher education. In this thesis, I engage with different forms of storytelling to highlight the relationships of mixed-status families in the United States. To accomplish this, I draw on the experiences of my mother...
The purpose of this paper was to discuss the theory of erotic capital proposed by Catherine Hakim and how this theory affects online advertising done by sex workers. Through analyzing 29 different pages relating to the commercial sex industry, I observed how sexual capital is utilized in marketing strategies and...
In the past, archaeological investigations have recovered material culture that have often been stored as museum property without a focused analysis or written report of the results. This study focuses on one such assemblage ofchipped stone projectile points from the Bachman Cave locality of southwestern Idaho that has been stored...
Animals aggregate and interact in nonuniform and nonrandom patterns, which lead to group level characteristics that have important evolutionary and ecological consequences. Network analysis provides a useful conceptual framework for linking animal interactions at all scales from dyads to communities, to populations and ecosystems. Despite exciting theoretical and applied advances...
Given the many significant roles that bacteria play in modern food manufacturing, it is crucial that we have a fundamental understanding of how bacterial communities assemble and behave in the food manufacturing environment. The focus of this dissertation was to investigate both the spatial and temporal distributions of microbial communities...
This thesis uses both feminist and new historic theories to argue that the women's romance novels The Last September (1929) by Elizabeth Bowen and The Country Girl's Trilogy (1960, 1962, 1964) by Edna O'Brien are tragic bildungsroman that subvert and challenge the Irish patriarchal marriage expectations of their respective time...
The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
The overall focus of this thesis is on the distribution of specific lipids and membrane proteins of the external and internal membranes of plant cells, in the context of the roles that those lipids and proteins may play in microbe-plant interactions. The work includes the development of several new tools,...
We do not know how to align a very intelligent AI agent's behavior with human interests. I investigate whether—absent a full solution to this AI alignment problem—we can build smart {\ai} agents which have limited impact on the world, and which do not autonomously seek power. In this thesis, I...
This dissertation argues for rooting genealogies and origin stories of Disability Studies and Mad Studies in women of color feminist scholarship-activism. Turning to women of color feminist work as “alternative origin stories” shifts Disability Studies and Mad Studies away from limiting and often racist eurowestern models of Madness/disability. Women of...
For the first time in several years, the El Niño-Southern
Oscillation did not dominate regional climate conditions
around the globe. A weak La Niña dissipated to ENSOneutral
conditions by spring, and while El Niño appeared
to be emerging during summer, this phase never fully
developed as sea surface temperatures in...
The Forest Service and the Bureau of Land Management propose to adopt coordinated ecosystem management direction for the lands they administer within the range of the northern spotted owl. This Supplemental Environmental Impact Statement (SETS) presents as alternatives the options, with slight modifications, developed by the Forest Ecosystem Management Assessment...