Background: There is increasing epidemiologic evidence that arsenic exposure in utero, even at low levels found throughout much of the world, is associated with adverse reproductive outcomes and may contribute to long-term health effects. Animal models, in vitro studies, and human cancer data suggest that arsenic may induce epigenetic alterations,...
Effective separation of lanthanides (Ln) from the minor actinides (MA) is a crucial technical challenge to closing the nuclear fuel cycle. This separation is a necessary prerequisite to transmute long-lived isotopes of Am and Cm, which will allow a reduction of the repository volume, thermal load, and radiological toxicity of...
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral
outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the
fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly.
Objectives: We examined potential associations between prenatal Hg exposure assessed...
Full Text:
Environ Health Perspect
doi: 10.1289/ehp.1408561
Note to Readers: If you need assistance accessing
Partitioning of trivalent actinides (in particular, americium and curium) from the
fission produced light lanthanides is a major concern of used nuclear fuel reprocessing for
the purposes of waste disposal. Several solvent extraction processes have been developed
to address these chemically difficult separations. The historically employed TALSPEAK
Process utilizes di-2-ethylhexyl...
Air pollution epidemiological studies suggest that elevated exposure to fine particulate matter (PM₂.₅) is associated with higher prevalence of term low birth weight (TLBW). Previous studies have generally assumed the exposure–response of PM₂.₅ on TLBW to be the same throughout a large geographical area. Health effects related to PM₂.₅ exposures,...
Background: Few studies examining the associations between long-term exposure to ambient air pollution and mortality have considered multiple pollutants when assessing changes in exposure due to residential mobility during follow-up.
Objective: We investigated associations between cause-specific mortality and ambient concentrations of fine particulate matter (≤ 2.5 μm; PM₂.₅), ozone (O₃),...
Full Text:
Environment Cohort (CanCHEC). Environmental Health Perspectives,
123(11), 1180-1186. doi:10.1289/ehp.1409276
BACKGROUND: Half the world’s population lives in urban areas. It is therefore important to identify
characteristics of the built environment that are beneficial to human health. Urban greenness
has been associated with improvements in a diverse range of health conditions, including birth
outcomes; however, few studies have attempted to distinguish...
Full Text:
Perspectives, 122(10), 1095-1102. doi:10.1289/ehp.1308049
10.1289/ehp.1308049
National Institute of
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly. Objectives: We examined potential associations between prenatal Hg exposure assessed...
Background: Arsenic is an immunotoxicant. Clinical reports observe the reactivation of varicella zoster virus (VZV) in people who have recovered from arsenic poisoning and in patients with acute promyelocytic leukemia that have been treated with arsenic trioxide. Objective: We evaluated the association between arsenic and the seroprevalence of VZV IgG...
BACKGROUND: Bisphenol A (BPA) is one of the most prevalent chemicals in daily-use materials; therefore, human exposure to BPA is ubiquitous. The estrogenicity of BPA is generally mediated by nuclear estrogen receptors (ERs). However, low concentrations of BPA stimulate seminoma cell proliferation by an uncertain mechanism that does not involve...
BACKGROUND: Half the world’s population lives in urban areas. It is therefore important to identify
characteristics of the built environment that are beneficial to human health. Urban greenness
has been associated with improvements in a diverse range of health conditions, including birth
outcomes; however, few studies have attempted to distinguish...
Full Text:
Environmental Health Perspectives doi:10.1289/ehp.1308049
Supplemental Material
Residential Greenness
Background: Few studies examining the associations between long-term exposure to ambient air pollution and mortality have considered multiple pollutants when assessing changes in exposure due to residential mobility during follow-up.
Objective: We investigated associations between cause-specific mortality and ambient concentrations of fine particulate matter (≤ 2.5 μm; PM₂.₅), ozone (O₃),...
Full Text:
Environment Cohort (CanCHEC)
Environ Health Perspect
DOI: 10.1289/ehp.1409276
Note to Readers: EHP
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral
outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the
fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly.
Objectives: We examined potential associations between prenatal Hg exposure assessed...
Full Text:
. doi:10.1289/ehp.1408561
10.1289/ehp.1408561
National Institute of Environmental Health Sciences
Exposure to urban outdoor air pollution is ubiquitous and low birth weight represents an important health disparity in the United States. While previous research suggests that exposure to outdoor air pollutants are associated with term low birth weight, few studies have evaluated the effects of multipollutant outdoor air exposures or...
Background: When conducting research with American Indian tribes, informed consent beyond conventional institutional review board (IRB) review is needed because of the potential for adverse consequences at a community or governmental level that are unrecognized by academic researchers. Objectives: In this article, we review sovereignty, research ethics, and data-sharing considerations...
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral
outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the
fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly.
Objectives: We examined potential associations between prenatal Hg exposure assessed...
Full Text:
: 10.1289/ehp.1408561
Note to Readers: EHP strives to ensure that all journal content is accessible to all
Childhood cancers are rare diseases that affect 188 children in Texas for every million born. Leukemia is the most common childhood cancer and accounts for roughly one third of childhood cancer cases. However, it is estimated that only 10% of childhood cancer cases can be explained by known risk factors....
s
Metrics
Comments
Related Content
Abstract
Introduction
Methods
Results
Discussion
Conclusions
Supporting Information
Acknowledgments
Author Contributions
References
Reader Comments (0)
Media Coverage (0)
Figures
Abstract
Perchlorate is a common aquatic contaminant that has long been known to affect thyroid function in vertebrates, including humans. More recently perchlorate has been shown...
Full Text:
. Environ Health Perspect. 2005; 113
(4):396–401. doi: 10.1289/ehp.7333 PMID: 15811828; PubMed Central PMCID
Background:
In the Ganges Delta, chronic arsenic poisoning is a health concern affecting millions of people who rely on groundwater as their potable water source. The prevalence of anemia is also high in this region, particularly among women. Moreover, arsenic is known to affect heme synthesis and erythrocytes and the...
BACKGROUND: Chronic exposure to arsenic is associated with skin lesions. However, it is not known whether reducing arsenic exposure will improve skin lesions.
OBJECTIVE: We evaluated the association between reduced arsenic exposures and skin lesion recovery over time.
METHODS: A follow-up study of 550 individuals was conducted in 2009-2011 on...