DNA is often described as the “blueprint for life”. In eukaryotes this information is contained within linear chromosomes of varying size and number. During cell division, the chromosomes must be faithfully segregated into each daughter cell to avoid disease and sustain life. This process is carried out by the kinetochore...
This research sought to identify the reasons physicians attributed for practicing in Oregon, the reasons for relocating out of Oregon, and the reasons for failures in recruiting physicians to Oregon. A random sample survey of 494 Oregon physicians identified the presence of economic and non-economic factors related to the recruitment...
PURPOSE Rural hospitals began to make significant changes in the 1990s by becoming integrated with larger health systems. The literature has correlated several key measures that determine the success of integrated health systems. These measures were quality, financial strength, community benefit, physician outcomes, and service changes. The purpose of this...
In response to genotoxic stress, ATR and ATM kinases phosphorylate H2A in fungi and H2AX in animals on a C-terminal serine.
The resulting modified histone, called γH2A, recruits chromatin-binding proteins that stabilize stalled replication forks or promote
DNA double-strand-break repair. To identify genomic loci that might be prone to replication...
Full Text:
. Lynch,a* Caitlin V. Mueller,a StevenFriedman,b Michael Freitag,b Zachary A. Lewisa
Department of
In response to genotoxic stress, ATR and ATM kinases phosphorylate H2A in fungi and H2AX in animals on a C-terminal serine.
The resulting modified histone, called γH2A, recruits chromatin-binding proteins that stabilize stalled replication forks or promote
DNA double-strand-break repair. To identify genomic loci that might be prone to replication...
In response to genotoxic stress, ATR and ATM kinases phosphorylate H2A in fungi and H2AX in animals on a C-terminal serine. The resulting modified histone, called γH2A, recruits chromatin-binding proteins that stabilize stalled replication forks or promote DNA double-strand-break repair. To identify genomic loci that might be prone to replication...
Shell-boring polychaetes pose economic risks for oyster aquaculture industries as they reduce the aesthetic quality of oyster products by creating unsightly mud-filled blisters on the inside of the shell. Recently there has been a reported uptick in infested oysters on commercial farms along the west coast of the US, which...
Transgenic biotechnology holds enormous potential as a tool to address global food insecurity. Transgenic food crops have been shown to increase food availability and food system security by incorporating disease, pesticide and drought resistance. Production costs of transgenic crops are lower due to the reduced need for costly pesticides and...
Ascorbic acid, or vitamin C, is well known as a co-factor for proline-hydroxylase and as an anti-oxidant. However, it is also capable of forming covalent bonds, particularly in the role of a nucleophile, henceforth termed 'ascorbylation'.
The ascorbylation of electrophiles can occur under physiological conditions. Furthermore, there are a number...
The federal government has spent considerable sums of money to
rehabilitate range lands administered by the Bureau of Land Management
(BLM). These investments have had varying effects on the production
and utilization of forage on these lands.
One of the most surprising results, according to BLM officials,
of the investments...
This dissertation is comprised of four studies on different elements of Populus biotechnology and genomic science: 1) growth improvement by recombinant DNA (rDNA) modification of gibberellin (GA) metabolism; 2) gene editing using zinc-finger nucleases (ZFNs); 3) induction of floral sterility by RNA interference (RNAi) of AGAMOUS (AG) gene homologs; and...
Dietary nitrate (NO3-), consumed primarily from leafy green and root vegetables, lowers blood pressure, improves vascular function and aerobic exercise performance. This performance-enhancing effect of nitrate supplementation is largely attributed to the increased bioavailability of the signaling molecule, nitric oxide (NO). Nitric oxide is a ubiquitous free radical signaling molecule...
Histones, as part of nucleosomes, are responsible for DNA packaging in chromosomes. They also affect DNA expression by a multitude of post-translational modifications, especially prevalent on the amino terminus of histones. Co-activator protein complexes “write”, “read”, or “erase” histone modifications, and in balance determine which sections of DNA are free...
Watching how Oregon State is working to combat some of the complex social issues that plague the world today by placing student success at the top of their strategic priority list, the Oregon State Investment Group (OSIG) believes that by leveraging capital markets we can play our part in helping...
Concurrent error detection (CED) is the detection of errors or faults in a circuit or data path concurrent with normal operation of that circuit. The general approach for CED is to calculate a check symbol for the inputs to the circuit under operation, predict the check symbol that will result...
Radiotelemetry was used to study the seasonal movements and habitat use of adult westslope cutthroat trout Oncorhynchus clarki lewisi in Roberts
Creek and Rail Creek, headwater tributaries of the John Day River, Oregon,
from September 2000 to December 2001. The objectives were to (1)
describe adult cutthroat trout life history...
Twenty-six Holstein and 18 Jersey multiparous cows in a randomized block design were assigned by calving date and breed to a non-anionic prepartum diet (CTRL) or a treatment diet containing a commercial anionic salt supplement (Animate®). Control and treatment diets were formulated to a dietary anion-cation difference (DCAD) of 21.3...