Here the diversity and phylogeny of the genus, Sthereus Motschulsky, 1845, and its nearest associates in the large subfamily Molytinae are explored through molecular and morphological characters. Sanger sequencing of five genes determined that Sthereus is not monophyletic. Instead, the one species in the genus Gastrotaphrus Buchanan 1936, G. barberi...
In recent decades the habitat of North American beaver (Castor canadensis) has expanded from boreal forests into pan-Arctic tundra ecosystems. It is unknown how the advance of beavers into Arctic watersheds will impact microbial communities responsible for the mineralization of organic matter (OM), which has implications for carbon cycling. To...
The past decade of research has potentiated a revolution in our understanding of mammalian health and evolution by revealing that the gut microbiome plays a central role in mammalian physiology. Our ability to unlock this potential hinges upon the identification of specific groups of gut microbes that elicit effects on...
Intertidal herbivores, such as isopods, help regulate and contribute to nutrient cycling and organic carbon flow through the trophic levels in estuaries and coastal ecosystems. Though much is known about the microbiomes of macrophyte leaves that serve as the primary food source for isopods, and (to a lesser extent) the...
Vibrio bacteria are commonly found in freshwater, marine, and estuarine environments. Members of this genus can exist in commensal relationships with marine animals or as planktonic bacteria, however, they are well known for their roles as pathogens towards humans and animals. In this dissertation, I investigated aspects of host-bacteria relationships...
Over the last ten years, clinical, pre-clinical and animal studies have shown associations between the microbiota and neurological functions. Recent work by the scientific community on the gut-microbiome-brain axis have revealed that gut dysbiosis and specific microbial taxa are associated with a myriad of neurological conditions, such as autism spectrum...
Investigations of 16S rRNA gene sequences hallmark modern microbiology. These sequences provide culture-independent insight into the abundance and distribution of microbiota and serve as a principle resource through which microbial community diversity is measured. Consequently, researchers rely on 16S gene sequences to test hypotheses rooted in ecology, evolution, and disease....
Biotic and abiotic processes at continent-ocean interfaces cycle a disproportionate mass of carbon and nutrients relative to their global surface area, and microbial activity is a principal determinant of organic and inorganic matter flux in these transition zones. Most studies using modern high-throughput ‘omics techniques to link microorganisms with costal...
Igneous oceanic crust encompasses ~60% of Earth’s surface and is composed of basalt glass and mafic, ultramafic, and felsic minerals. A vast marine aquifer lies within the crust, exchanging geochemically altered fluids with seawater from the overlying ocean at ridge crests, flanks, seamounts, and outcrops where permeable crust is exposed....
The complex, dynamic nature of microbial communities in both natural and engineered environments complicates the work of scientists and engineers who wish to channel microbial interactions for societal good. The successful management of these communities towards engineering goals is dependent on developing predictive linkages between community structure and functional outputs....
Limnology is undergoing a transition to high-throughput -omic analysis of freshwater
bacterial communities. An important first step in making the transition is to
characterize several genomes that can be used as references to guide metagenome
assembly and analysis. Here I characterize four new freshwater cyanobacterial
genomes, a pair of lake...
BACKGROUND: The release of antibiotics into aquatic environments has made the treatment of wastewater
containing antibiotics a world-wide public health problem. The ability of microbial fuel cells (MFCs) to harvest
electricity from organic waste and renewable biomass is attracting increased interest in wastewater treatment.
In this paper we investigated the...
PURPOSE: The in vitro inhibitory effect of Docetaxel (DTX) and Everolimus (EVR) alone and together in
poly(ethylene glycol)-block-poly(D,L-lactic acid) (PEG-b-PLA) nanocarriers on angiogenic
processes and acute toxicity in mice was evaluated.
METHODS: PEG-b-PLA DTX and/or EVR nanocarriers were characterized for size, drug loading, stability,
and drug release. Cell proliferation, tubule...
Metagenomics has revealed that the marine microbial biosphere is immensely more diverse than originally considered, and is an almost untapped reservoir for the potential discovery of microbial natural products. Despite numerous advances in culturing, biosynthetic engineering and genomic-based screening efforts to uncover much of this diversity in relatively accessible environments,...
Western Oregon is home to native Rhododendron species and is the center for cultivated
Rhododendron production in the United States. These Rhododendron spp. are known to
be infected with fungal endophytes. However, the community structure of these
endophytes in native and cultivated Rhododendron is poorly understood. Our study
targeted the...
Mat-forming ectomycorrhizal (EcM) fungi represent a prevalent constituent of many temperate forest ecosystems and create dramatic changes in soil structure and chemistry. EcM mat soil have been shown to have increased microbial respiration rates and have been hypothesized to harbor unique assemblages of fungi and bacteria. The objectives of this...
Capturing the spatial distribution of high-intensity rainfall over short-time intervals is critical for accurately assessing the efficacy of urban stormwater drainage systems. In a stochastic simulation framework, one method of generating realistic rainfall fields is by multiplicative random cascade (MRC) models. Estimation of MRC model parameters has typically relied on...
Capturing the spatial distribution of high-intensity rainfall over short-time intervals is critical for accurately assessing the efficacy of urban stormwater drainage systems. In a stochastic simulation framework, one method of generating realistic rainfall fields is by multiplicative random cascade (MRC) models. Estimation of MRC model parameters has typically relied on...
This monograph presents a proof grammar for a formal language containing property symbols of every finite type. The proof grammar is thus applicable to any finite level higher-order logic.
The unique features of this system are: first, its mode of presentation as a recursive discourse grammar rigorously constructed from the...
Numerous attempts have been made to identify the flavor
compounds in Blue cheese, however, duplication of Blue cheese
flavor has not yet been accomplished. Therefore, it was desirable
to make a qualitative and quantitative investigation of Blue
cheese flavor compounds and to study the effect of certain microorganisms
on Blue...