Mammalian female reproduction requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from neurons in the preoptic area (POA) of the hypothalamus, initiated by elevated estradiol (E₂). Rising E₂ activates a subset ofsexually dimorphic Kisspeptin neurons in the female, located in the anteroventralperiventricular nuclei (AVPV). Conversely, E₂ negative feedback is mediated by...
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role in puberty
Generating kisspeptin cell
lines to investigate their role
in reproduction
Dakota
Mammalian female reproduction requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from neurons in the preoptic area (POA) of the hypothalamus, initiated by elevated estradiol (E₂). Rising E₂ activates a subset ofsexually dimorphic Kisspeptin neurons in the female, located in the anteroventralperiventricular nuclei (AVPV). Conversely, E₂ negative feedback is mediated by...
Ovulation requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from preoptic hypothalamic neurons, initiated by elevated ovarian estradiol (E₂). Rising estradiol activates a subset of sexually dimorphic kisspeptin (Kiss-1) neurons in the female, located in the anteroventral periventricular nuclei (AVPV). Conversely, estradiol negative feedback on GnRH secretion is mediated by a...
Mammalian female reproduction requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from neurons in the preoptic area (POA) of the hypothalamus, initiated by elevated estradiol (E₂). Rising E₂ activates a subset ofsexually dimorphic Kisspeptin neurons in the female, located in the anteroventralperiventricular nuclei (AVPV). Conversely, E₂ negative feedback is mediated by...
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Steroid-Mediated Initiation of Puberty
DakotaC. Jacobs1, Jadwiga M. Giebultowicz2,and Patrick E
The story of Leo Szilard has not been told in its full complexity. This is especially so of the role imagination played in Szilard’s worldview. Szilard, like many other scientists in the mid-twentieth century, worked on the Manhattan Project. Like these other wartime participants, the work and relationships formed during...
These essays are an attempt to rebuild memories that explore the nature of work and family. They explore how work knocks against the joints of the body and against the joints between family members, and, as time passes, how the next generation inherits the family line of work only to...
This paper deals with finite abstract Witt rings in the case where
-1 = 1 in the square class group.
The results also apply to Witt rings
of quadratic forms over fields where √-1
is in the field.
The concept
of relative rigidity is studied in finite abstract Witt rings...
Artificial lipid bilayer technologies are effective models for studying cell membrane properties. Droplet bilayers rely on microfluidics and provide advantages over other bilayer methods due to their compatibility with automated development systems that increase yield while minimizing cost. This paper describes the implementation of bilayer technologies using membrane protein channels...
Affective reactions to daily stressors are known mechanisms through which daily stressors impact health and well-being (e.g., Charles et al., 2013; Piazza et al., 2013; Sin et al., 2015; Stawski et al., 2019). Therefore, understanding what may promote resilience or vulnerability to such affective reactions is imperative. Theoretical perspectives (Almeida,...
Daily social stressors are important everyday experiences that influence an individual’s daily health and well-being across the lifespan. One pathway through which daily social stressors influence health and well-being is through changes in positive and negative affect. The vast majority of previous research has focused on individual difference characteristics to...
Over the last 60 years, supplemental strength and conditioning for improving sport performance has gone from being nearly non-existent to a cornerstone feature of elite collegiate, amateur, and professional athletics. Concurrent with this profession-related evolution, technologies for monitoring and tracking physical performance have become more prevalent and useful. As an...
Ian Angell, in the New Barbarian Manifesto, said “A ‘brave new world’ is being forced upon unsuspecting societies by advances in information technology.” It would seem then, that technological advances happen automatically and have a life of their own. There is a logic to technological advancements that is outside human...
People involved in a nuclear activity, whether they are developing it, benefiting from it, or opposing it, see inherent connections between various aspects of nuclear science and technology. This thesis investigates three nuclear sites: a university research reactor, a dual-purpose reactor that produced plutonium for the U.S. military and electricity...
The atomic age was enacted by many scientists as a way to realize health and human rights. Human rights were conceived in this context as rights to economic development, science education, and nuclear medicine. The United States Atomic Energy Commission (AEC) acted hand in hand with UN agencies and educators...
Beginning in the late-nineteenth century, several dialogues emerged concerning life on Mars. Some supported the notion of an inhabited Mars, citing recent observations of the planet, while others, pointing to a lack of concrete evidence, denied the validity of such a bold hypothesis. The dialogues within and between different...
The Second World War was not just a military struggle but also a struggle between two different agriculture, food distribution, and nutrition systems in the United Kingdom and Nazi Germany. At the start of the war, both countries understood that food and nutrition would play an important role and carefully...
In 1947, scientists from the University of California departed for a fifteen-month expedition to Africa. Jessie Camp, wife of the head paleontologist Dr. Charles L. Camp, had no official position on the expedition. Yet in performing her traditional domestic duties, she greatly contributed to the overall success of the expedition....
The Hanford Nuclear Reservation drew public ire during the 1980s and 1990s when activist groups forced the declassification of 19,000 documents and discovered proof of accidental and intentional releases of radioactive materials into the environment. These releases had been kept from the public. Although many locals had for decades wondered...
Traditional Ecological Knowledge (TEK) is a Knowledge-belief-practice system acquired through intergenerational direct and indirect observations representing past and current understandings of environments and integrates Indigenous value systems. TEK has become a popular topic recently as Indigenous stewarded lands contain more biodiversity and are more adaptable. It is critical for Indigenous...
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Lara Jacobs, Committee Member, representing Michigan State University Office of the
Provost
Evapotranspiration (ET) is the process by which water is transferred from land to the atmosphere. ET is the second most important component of a hydrologic budget and remains difficult to estimate. The primary objective of this project was to determine the limitations of estimating ET from water table elevation fluctuations...
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ABSTRACT OF THE THESIS OF
Jacob K. Kollen for the degree of Master of Science in Water Resources
Nitrogen (N) fertilizer application can promote nitrate leaching below the rooting zone and into groundwater drinking water sources in many agricultural settings. The proper management of N application can minimize non-point source nitrate pollution to groundwater. This study examines the potential for enhanced efficiency fertilizers, specifically urea treated with a...
The coast of Oregon is highly dynamic, with beach and dune morphodynamics constantly evolving in response to physical and ecological forcing at scales ranging from seconds to decades and meters to tens of kilometers. Evaluating spatial and temporal trends in shoreline evolution is paramount in understanding and eventually developing a...
The effect of land uses on neighboring property values is of critical interest to urban planners, developers, and citizens. Property values are in part defined by built structure and lot characteristics, locational attributes (e.g., proximity to amenities and disamenities), and other features such as views from a property. The effects...
Pin and hanger assemblies are a common type of connection used in past engineering practice for steel girder bridges. The connection consists of pins, hanger plates, and girder ends. The connection detail was used widely between 1930 and 1980. The connections are considered fracture critical and nonredundant because connection failure...
An evaluation was made during midsummer 1972 to measure damage by the carpenterworm, Prionoxystus robiniae, and the ash borer, Podosesia syringae, to green ash in windbreaks in North Dakota. Intensity of infestation was determined in four land resource areas and four age classes of windbreaks. Of the 96 windbreaks examined...
A survey to determine distribution and intensity of cankers and associated damage in North Dakota windbreak plantings of Russian-olive and Siberian elm was conducted in 1972. Four hundred and thirty-five (76 percent) of 574 Russian-olive examined had cankers, and 552 (72 percent) of 769 Siberian elm examined had cankers. Cankers...
Two ecologically important lamprey species found in the endorheic Goose Lake Basin face conservation threats; however, relatively little is known about their habitat needs or spatial distribution. Lamprey and their habitat are often found to be patchy; to evaluate these relationships for the lamprey in this basin, I utilized a...
In this dissertation, the process of computational modeling of amorphous oxide materials is studied. Amorphous oxides have random atomic arrangements with no long-range structural order which makes it difficult to study structure-property relationships. Despite the difficulties, amorphous oxides have great uses as semiconductors and dielectrics in thin-film transistors. The ability...
In 1971, about 2,000 acres (Figure 1) of mixed hardwoods were infested by the forest tent caterpillar, Malacosoma disstria Hubner, on the Totten Indian Reservation south of Devil's Lake, North Dakota. An aerial and ground survey of this area was made on June 15, 1972.
Defoliation could not be detected...
Attempts to site nuclear waste storage facilities are highly contentious. Given that nuclear related facilities are the most commonly opposed types of proposed land uses, one might expect to observe strong contentious interactions between proponents and immediate community members. In some cases, what is expected is not necessarily observed; why?...
Salmonids in arid high-elevation streams find themselves at the fringe of their tolerance range. Under the conditions they endure in such environments, long-distance migratory movements among widely dispersed habitats may be an important mechanism for some fish to persist, and even thrive. The Donner und Blitzen (Blitzen) River redband trout...
Due to the advancement of incredibly low power microcontrollers and small form factor integrated circuits, energy harvesting can be considered as an alternative, low power source for remote ocean sensing and measurements. To demonstrate the effectiveness of harvesting thermoelectric energy contained in the temperature differential between ocean surface water and...
Due to increasing populations, food production must increase significantly to be sustainable. The Internet of Things has been shown to have potential in the field of agriculture to make farming practices more efficient. However, for IoT to be properly integrated into agriculture, sensors must be applied within the field and...
This project concerns the design, layout, assembly, debugging, and testing of a Printed Circuit Board (PCB) that autonomously, reliably, and effectively conducts Cyclic Voltammetry (CV) measurements. CV is an electrochemical procedure done to analyze, quantize, and visualize reversible reduction-oxidation reactions, often used in medical devices to monitor the levels of...
The gut microbiome of all mammals is composed of a diverse commune of microorganisms including bacteria, fungi, archaea, protozoa and viruses 1. Studies have shown a symbiotic relationship between the gut microbiome and host physiology, with there being implications in health and disease progression 2. In captive animals, there has...
Over 90 percent of the soy, cotton, and corn sold in the United States are genetically modified crops (GM crops). However, there was a 209 percent growth in USDA certified organic food from 2005-2015, reflecting a growing interest in non-GMO food. The policy debate over GM crops takes place between...
Despite extensive research on the historical and technical aspects of national space policy, little has attempted to understand the links between technological evolution in NASA’s spaceflight program in relation to its administrative, political and economic context. This essay explores these connections in the development and evolution of core systems in...
This work investigates the in-tube condensation of low global warming potential (GWP) zeotropic refrigerant mixtures R448A, R450A, R452A, R454B and R454C. These refrigerants have been proposed for a wide range of commercial heating, ventilation, air-conditioning applications, but their heat and momentum transport phenomenon were not well understood. Thus, in this...
There is an urgent need to lower the concentration of sulfur in diesel fuels. Growing concern over environmental effects caused by burning sulfur-containing diesel has led the world to higher standards in fuel refinement. Because of these lower standards, many techniques have been researched to remove sulfur containing compounds or...
The problem was to determine (1) to what extent the Industrial
Arts Program had expanded in facilities, enrollment and teachers
from 1952 to 1962, (2) to compare the status of the Industrial Arts
Program in 1952 with that in 1962 to determine growth and trends,
and (3) to determine to...
The Demonstration of Ecosystem Management Options (DEMO) study is a large-scale, multi-year, interdisciplinary project examining the effects of various levels and patterns of green-tree retention on multiple forest features. Six retention levels and patterns were examined and replicated across six blocks of predominately Douglas-fir forested land in western Oregon and...
This study examined changes in flour functionality during storage of grain and subsequent aging of flour milled from the grain. Freshly harvested grain was stored for 24 weeks and flour milled from the grain at specified time intervals after harvest (0, 3, 6, 12, and 24 weeks). For each milling...
Gold nanostars are a relative newcomer to the nanoparticle scene, and their unique properties make them very desirable for spectroscopic applications. These nanoparticles, with their sharp tips, create electric field enhancements that interact with light in an advantageous way. This Thesis outlines our in-depth study of gold nanostar synthesis, the...