Modern wireless System-on-Chips (SoCs), such as mobile handsets, sensor networks, and mm-wave systems, integrate an entire RF system on a single CMOS chip. Such highly complex systems require significant on-chip digital signal processing to help improve the performance of highly sensitive analog/RF components. The IC
market being competitive, the ability...
The study was carried out in a village named MGR Thittu in the vicinity of the Pichavaram mangroves in the state Tamil Nadu in India. The objectives of the study were to review the current status of mangroves in Tamil Nadu, study the fisherfolk’s perceived role of mangroves on their...
A scheme is presented for retrieving aerosol properties for ocean regions from reflected sunlight at both the visible and near infrared wavelengths measured by the NOAA advanced very high resolution radiometer (AVHRR). For the Indian Ocean Experiment (INDOEX), aerosols were presumed to be a mixture of a continental haze that...
This dissertation delves into understanding, characterizing, and addressing dataset shift in deep learning, a pervasive issue for deployed machine learning systems. Integral aspects of the problem are examined: We start with the use of counterfactual explanations in order to characterize the behavior of deep reinforcement learning agents in visual input...
Every year, from December to April, anthropogenic haze spreads over most of the North Indian Ocean, and South and Southeast Asia. The Indian Ocean Experiment (INDOEX) documented this Indo-Asian haze at scales ranging from individual particles to its contribution to the regional climate forcing. This study integrates the multiplatform observations...
In previous papers by Awrejcewicz in 1986 and Narayanan and Jayaraman in 1991, it was claimed that the nonlinear oscillator with dry friction exhibited chaos for several forcing frequencies. The chaos determination was achieved using the characteristic exponent of Lyapunov which requires the right-hand side of the differential equation to...
The Indian Ocean Experiment (INDOEX) had as a primary objective
determining the radiative forcing due to anthropogenic aerosols over
climatologically significant space and time scales: the Indian Ocean during the
winter monsoon, January-March. During the winter monsoon, polluted, low-level
air from the Asian subcontinent blows over the Arabian Sea and...
A new approach to the discovery of high absorbing semiconductors for solar cells was taken by working under a set of design principles and taking a systemic methodology. Three transition metal chalcogenides at varying states of development were evaluated within this framework. Iron pyrite (FeS₂) is well known to demonstrate...
The atmospheric radiative transfer model MOCARAT was developed and is presented in this thesis. MOCARAT employs a Monte Carlo Technique for the accurate modeling of band radiances and reflectances in an atmospheric system with a ruffled ocean surface as a lower boundary. The atmospheric radiative transfer is modeled with consideration...
The effect of ultra-high pressure on the thermal emf of a
chromelialumel thermocouple is investigated using an indirect
method which does not require a direct knowledge of the temperature
of the pressurized junction. The unknown temperature is written
parametrically as a function of a directly measured quantity, the
electrical power...
Escherichia coli 16S-like ribosomal RNAs from
eubacterial, archaebacterial and eukaryotic organisms have
several universally conserved sequence zones which are
proposed to be single-stranded. A clear function for all
of these regions has not yet been defined. To evaluate the
roles of these sequence zones in protein synthesis,
knowledge of their...
Dimensional stability of wood-based composites with changing moisture content remains an important challenge in the industry for many applications. Wood modification technologies have shown significant improvement in dimensional stability by altering the chemistry of the wood substrate, or by filling the available space in the wood microstructure that otherwise would...
Goats were the first livestock species to be domesticated by humans and continue to function as a key source of protein and economic value for many communities. In the sixteenth century, Spanish colonists brought goats to the Americas. Unlike other nations, the United States did not maintain a significant market...
Purpose: Model-based dose calculation algorithms (MBDCAs) have become clinically available within the past several years in commercially available brachytherapy planning systems. This work investigates the application of a 510(k) approved MBDCA Acuros™ BV and establishes a reproducible method of validation. The research is broken into three primary research goals. The...
The in vitro effects of cortisol in regulating salmonid B cell functions were
investigated. B cells at three distinct stages of differentiation were examined for
cortisol sensitivity. B lymphocyte responses were examined 1) during the early stage
of the precursor, 2) during the intermediate stage of differentiation associated with
clonal...
Electric power needs will only grow over the next decades as more humans ascend from poverty into the middle class. Currently, the majority of electric power is generated by burning fossil fuels. To help mitigate the undesirable effects of burning fossil fuels research is being done to increase the efficiency...
In this dissertation, the spectroscopic properties and thermodynamic stability of a class of materials known as metal oxo and hydroxo clusters are studied. In aqueous solutions, many metals can aggregate into discrete clusters of metals bridged by oxo or hydroxo ligands. These clusters are of particular interest to us for...
Simulation is a powerful analytical tool for designing or experimenting with complex systems. Simulation has been defined as the process of designing a model of a real system and conducting experiments with this model either to understand the system’s behavior or to evaluate various strategies for operating it (Pegden et...
The effective radius of water cloud droplets is retrieved using remotely sensed passive microwave and visible data collected by aircraft during the Indian Ocean Experiment. The purpose of this study is to assess the aerosols’ effect on cloud microphysical and radiative properties. To study this effect, we investigate the relationships...
Empirical estimates of the aerosol indirect radiative forcing often rely on threshold cloud retrievals applied to multispectral satellite imagery data. In such retrievals, pixels having radiances that surpass prescribed thresholds are assumed to be overcast even if they are only partially cloud covered. This assumption leads to cloud visible optical...
The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
Autoinduction (AI), the response to self-produced chemical signals,
is widespread in the bacterial world. This process controls
vastly different target functions, such as luminescence, nutrient
acquisition, and biofilm formation, in different ways and integrates
additional environmental and physiological cues. This diversity
raises questions about unifying principles that underlie all
AI...
The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...
Retrievals of cloud properties from satellite imagery often invoke the assumption that the fields of view are overcast when cloud-contaminated, even though a significant fraction are only partially cloud-covered. The overcast assumption leads to biases in the retrieved cloud properties: cloud amounts and droplet effective radii are typically overestimated, while...
Advanced Very High Resolution Radiometer (AVHRR) 4-km data collected over the northeastern Atlantic off the coast of the Iberian Peninsula for May to August 1995 were used to investigate the feasibility of empirically deriving estimates of the aerosol indirect radiative forcing. A retrieval scheme was used to derive cloud visible...
Advanced Very High Resolution Radiometer (AVHRR) 4-km data were collected over the northeast Atlantic for May–August 1995–1999. Aerosol optical depth at 0.55 μm was retrieved in pixels identified as being cloud-free ocean. In pixels identified as containing clouds from single-layered, low-level cloud systems over oceans, the following cloud properties were...
A time history of the calibration coefficients for channels 1 and 2 of the Advanced Very High Resolution Radiometer (AVHRR) on the NOAA-12 and NOAA-15 spacecraft is presented. The history is based on reflectances observed for the interior zones of the Antarctic and Greenland ice sheets previously obtained with the...
Reproductive and endocrine disruption is commonly reported in aquatic species exposed to complex contaminant mixtures. We previously reported that Atlantic killifish (Fundulus heteroclitus) from the chronically contaminated Newark Bay, NJ, exhibit multiple endocrine disrupting effects, including inhibition of vitellogenesis (yolk protein synthesis) in females and false negative vitellogenin biomarker responses...
Clouds and the Earth’s Radiant Energy System (CERES) uses a suite of instruments on the Terra and Aqua satellites combined with analyzed weather data and information on surface conditions to estimate surface radiative fluxes. CERES estimates for the Terra satellite were compared with measurements of the surface radiative fluxes collected...
Visible and near infrared reflectances from NOAA-14 Advanced Very High Resolution Radiometer (AVHRR) daytime passes are used to derive optical depths at 0.55 μm, an index of aerosol type, continental or marine, and the direct effect of the aerosol on the top of the atmosphere and surface solar radiative fluxes...
Observed declines in native pollinator species worldwide has generated concern and focused research into the disturbances, past and present, which may have contributed to these losses. In grasslands, for example, habitat degradation and fragmentation from historical and current crop production and livestock grazing has left only a few remnants of...
Complex organic transformations, such as the addition of pyrrole to ketene using planar chiral organocatalyst (*PPY), the four-component anhydride- Manniach reactions, and the site-selective desymmetrization of meso-1,2-diol, are remarkable synthetic reactions that provide high yield and high selectivity. However, the exact mechanism and origins of stereocontrol for theses synthetic organic...
Peroxiredoxins (Prxs) are dominant peroxide-reducing enzymes with two important roles: they protect all organisms from oxidative damage induced by peroxides, and in eukaryotes, they participate in hydrogen peroxide signaling pathways. This dissertation presents studies aimed at the biophysical characterization of select Prxs and a Prx reductase to elucidate their structure-function...
Ligand activation of the aryl hydrocarbon (AHR) has profound effects upon the immunological status of the gastrointestinal tract, establishing and maintaining signaling networks, which facilitate host-microbe homeostasis at the mucosal interface. However, the identity of the ligand(s) responsible for such AHR-mediated activation within the gut remains to be firmly established....
Full Text:
. Lee, J., Jayaraman, A. & Wood, T. K. Indole is an inter-species biofilm signal mediated by SdiA. BMC
Observations of sunlight reflected from regions of sun glint are used to check the relative calibration of spectral radiances obtained with imaging radiometers. Reflectances at different wavelengths for sun-glint regions are linearly related. Provided that the atmosphere is reasonably transparent at the wavelengths, the aerosol burden is reasonably light, 0.64-μm...
Research suggests that entrepreneurs tend to seek to maximize utility when considering whether to pursue a new venture opportunity. However, when choosing whether to persist with their current venture or not, utility maximization may not be of primary importance. Using a conjoint experiment, we examine the difference between policies in...
Imaging Ca²⁺ dynamics in living systems holds great
potential to advance neuroscience and cellular biology. G-GECO1.1
is an intensiometric fluorescent protein Ca²⁺-biosensor with a Thr-Tyr-Gly chromophore. The protonated chromophore emits green
upon photoexcitation via excited-state proton transfer (ESPT). Upon
Ca²⁺ binding, a significant population of the chromophores becomes
deprotonated. It...
The advent of scientific shrimp farming in India during 1990-91 was a turning point of shrimp production
in the country. Though scientific shrimp farming system renders higher level of production than the
existing traditional farming system, it is subject to certain criticisms especially for generating negative
environmental externalities. The conversion...
The gut microbiome has been previously implemented in a number of diseases. Of note is its substantial role in metabolic syndrome, which encapsulates a group of conditions that increase the risk of cardiovascular disease, type 2 diabetes, and stroke. Understanding the causal relationships between the gut microbiome and host processes...
A water-soluble complex containing ergosterol together with
a component of yeast has been isolated. The complex can be isolated
from commercial yeast extract to which ergosterol has been
added or directly from whole yeast cells. The complexing agent
from yeast extract is also capable of solubilizing cholesterol and
a long...
Structure-specific synthesis processes are of key importance to the growth of polymorphic functional compounds such as TiO₂, where material properties strongly depend on structure as well as chemistry. The robust growth of the brookite polymorph of TiO₂, a promising photocatalyst, has been difficult in both powder and thin-film forms due...
The purposes of this study were to assess mental
health counselors' knowledge of AIDS and to determine the
effect of various independent variables upon knowledge. The
variables used were gender, professional contact with PWAs,
personal contact with PWAs, age, sexual preference, AIDS
training, and personal acquaintance with a person who...
Sepsis, caused by bacterial release of endotoxin, is a serious blood infection that causes uncontrolled systemic immune response. In North America alone, sepsis kills between 220,000 and 380,000 people each year, more than prostate cancer, breast cancer, and HIV/AIDS combined. Sepsis treatment is complicated and often requires prolonged hospital stays,...
The purpose of this research was to examine the feasibility of carbon dioxide (CO2) laser perforation and its potential utilization as a novel skin pretreatment for the sugar infusion process of IQF (individually quick frozen) blueberries. In the first study, IQF blueberries were treated with varying degrees of laser perforation...
Fluorescent proteins (FPs) are luminescent biomolecules that emit characteristic hues upon irradiation. A group of calmodulin (CaM)-green FP (GFP) chimeras have been previously engineered to enable the optical detection of calcium ions (Ca²⁺). We investigate one of these genetically encoded Ca²⁺ biosensors for optical imaging (GECOs), GEM-GECO1, which fluoresces green...
The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that is a member of the basic helix-loop-helix PER-ARNT-SIM (bHLH/PAS) protein family of cellular sensors. The AHR is conserved across multiple animal phyla and is required for proper vertebrate development. A structurally diverse group of chemicals, including polycyclic aromatic...
Melanocytes are dendritic, pigment-producing cells located in the skin and are responsible for its protection against the deleterious effects of solar ultraviolet radiation (UVR), which include DNA damage and elevated reactive oxygen species (ROS). They do so by synthesizing photoprotective melanin pigments and distributing them to adjacent skin cells (e.g.,...
Xanthan gum, a naturally produced polysaccharide, is biocompatible, and it is commonly used as a food additive. When combined with trivalent ions, such as chromium (III), a gel can form. Various concentrations of xanthan gum and chromium (III) nitrate were combined to evaluate the sol-gel transition of this system. Samples...