Current studies suggest that perfluorinated organic compounds, such as fluorotelomer alcohols (FtOHs) in the troposphere, may be precursors of perfluorocarboxylic acids and perfluorosulfonates in remote regions. Fluorinated organic compounds were investigated in archived extracts collected from remote locations in Okinawa, Japan (HSO) and Mount Bachelor, Oregon (MBO) during the springs...
Atmospheric measurements of semivolatile organic compounds (SOCs) were made at Mt. Bachelor Observatory (MBO), located in Oregon’s Cascade Range, to understand the trans-Pacific and regional transport of SOCs from urban areas. High volume air sampling (~644 m³ for 24 hour periods) of both the gas and particulate phases was conducted...
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Transport of PAHs, PCBs, and FTOHs in the Western U.S.
Authors:
Toby Primbs, ArkadiuszPiekarz
Atmospheric measurements of semivolatile organic compounds (SOCs) were made at Mt. Bachelor Observatory (MBO), located in Oregon’s Cascade Range, to understand the trans-Pacific and regional transport of SOCs from urban areas. High volume air sampling (~644 m³ for 24 hour periods) of both the gas and particulate phases was conducted...
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9
10
Toby Primbs1, Arkadiusz Piekarz1, Glenn Wilson2, David Schmedding2, Carol Higginbotham3, 11
Atmospheric measurements of semivolatile organic compounds (SOCs) were made at Mt. Bachelor Observatory (MBO), located in Oregon’s Cascade Range, to understand the trans-Pacific and regional transport of SOCs from urban areas. High volume air sampling (~644 m³ for 24 hour periods) of both the gas and particulate phases was conducted...
Per- and polyfluoroalkyl substances (PFAS) are a group of anthropogenic compounds gaining notoriety as contaminants of emerging concern. With the frequent detection of PFAS in the environment, drinking water, and consumer products, awareness and concern from the public regarding PFAS is increasing. The two most notorious PFAS are perfluorooctanoate (PFOA)...
The relative influences of trans-Pacific and regional atmospheric transport on measured concentrations of polycyclic aromatic hydrocarbons (PAHs), PAH derivatives [Nitro- (NPAH) and Oxy-(OPAH)], organic carbon (OC), and Particulate Matter (PM) less than 2.5 μm in diameter (PM₂.₅) were investigated in the Pacific Northwest, USA in 2010-2011. Ambient high volume PM₂.₅...
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LAFONTAINE1, JILL SCHRLAU2, JACK BUTLER3, YULING JIA2, BARBARA HARPER3¥,4,
STUART HARRIS3¥, LISA M. BRAMER5
Polycyclic aromatic hydrocarbons (PAHs) are a known class of chemicals that are linked to a multitude of adverse health outcomes. There are over 1,500 of these chemicals across various families and subgroups. 16 of these PAHs, known as parent PAHs, are identified by the EPA for focused risk assessment within...
The relative influences of trans-Pacific and regional atmospheric transport on measured concentrations of polycyclic aromatic hydrocarbons (PAHs), PAH derivatives [Nitro- (NPAH) and Oxy-(OPAH)], organic carbon (OC), and Particulate Matter (PM) less than 2.5 μm in diameter (PM₂.₅) were investigated in the Pacific Northwest, USA in 2010-2011. Ambient high volume PM₂.₅...
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.; Piekarz, A.; Wilson, G.; Schmedding, D.; Higginbotham, C.; Field, J.; Simonich, 477
S. M., Influence of
The relative influences of trans-Pacific and regional atmospheric transport on measured concentrations of polycyclic aromatic hydrocarbons (PAHs), PAH derivatives [Nitro- (NPAH) and Oxy-(OPAH)], organic carbon (OC), and Particulate Matter (PM) less than 2.5 μm in diameter (PM₂.₅) were investigated in the Pacific Northwest, USA in 2010-2011. Ambient high volume PM₂.₅...
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2
, BARBARA HARPER
3¥,4
,
STUART HARRIS
3¥
, LISA M. BRAMER
5
, KATRINA M. WATERS
6
, ANNA
The relative influences of trans-Pacific and regional atmospheric transport on measured concentrations of polycyclic aromatic hydrocarbons (PAHs), PAH derivatives [Nitro- (NPAH) and Oxy-(OPAH)], organic carbon (OC), and Particulate Matter (PM) less than 2.5 μm in diameter (PM₂.₅) were investigated in the Pacific Northwest, USA in 2010-2011. Ambient high volume PM₂.₅...
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., Butler, J., Jia, Y., Harper, B., Harris, S., ... & Simonich,
S. L. M. (2015). Relative Influence of
In this report, three studies are presented that utilize computations to predict transformations, identities, and properties of environmental organic molecules. Each study shows how computations can lead to models of chemical behavior. The importance of this research is rooted in the need for understanding how human behavior and health intersect...
The atmospheric transport of anthropogenic semivolatile organic compounds (SOCs) from Asian sources to the Western U.S. was investigated. In addition, the SOC extraction method was optimized. Hansen solubility parameter plots were used to aid in the pressurized liquid extraction (PLE) solvent selection of air sampling media in order to minimize...
The relative influences of trans-Pacific and regional atmospheric transport on measured concentrations of polycyclic aromatic hydrocarbons (PAHs), PAH derivatives [Nitro- (NPAH) and Oxy-(OPAH)], organic carbon (OC), and Particulate Matter (PM) less than 2.5 μm in diameter (PM₂.₅) were investigated in the Pacific Northwest, USA in 2010-2011. Ambient high volume PM₂.₅...
A method was developed for the measurement of 19 parent PAHs (PAHs) and 34 hydroxylated
PAHs (OH-PAHs) in urine and personal air samples of particulate matter less than 2.5 um in
diameter (PM[subscript 2.5]) using GC-MS and validated using NIST SRM 3672 (Organic Contaminants in
Smoker’s Urine) and SRM 3673...
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., Schrlau, J., Yuling, J., Harper, B., Harris, S., Harding, A., &
Simonich, S. L. M. (in press
Historic and current use pesticides (HUPs and CUPs), with respect to use in the United States and Canada, were identified in trans-Pacific and regional air masses at Mt. Bachelor Observatory (MBO), a remote high elevation mountain in Oregon’s Cascade Range located in the United States, during the sampling period of...
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location of Mt. Bachelor Observatory (MBO) (43.98°N 121.69°W, 2763
m above sea level) in Oregon’s Cascade
Atmospheric fine particulate matter (PM2.5) has been linked to the death of 7 million people per year around the planet. The organic portion of PM2.5 is responsible for increases in oxidative stress, inflammation, mutation and carcinogenesis. Anthropogenic activity releases more organic material into the atmosphere, and has increased the amount...
Female dairy cattle are particularly prone to infertility/subfertility with pregnancy rates ranging as low as 27% to a high 40%. On average it takes more than one breeding/insemination event for dairy cattle to become pregnant. This results in a loss of the number of calves a female would have per...
The trans-Pacific atmospheric transport of particulate matter (PM)-bound polycyclic aromatic hydrocarbons (PAHs) to remote sites in western North America has been well documented and has triggered research questions regarding to atmospheric transformation of PM-bound PAHs and the potential impacts on human health from their inhalation exposure. In this dissertation, field...
This research is the first to quantify complex PAH mixtures in NIST SRMs using comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC×GC/ToF-MS), with and without extract cleanup, and reports previously unidentified PAH isomers in the NIST SRMs. We tested a novel, high orthogonality GC column combination (LC-50×NSP-35), as...
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. Genualdi, S. M. Simonich, Environ. Toxicol. Chem., 2008, 27. 1267-1272.
[36] T. Primbs, A. Piekarz, G
The heterogeneous reactions of ambient particulate matter (PM)-bound polycyclic
aromatic hydrocarbons (PAHs) and nitro-PAHs (NPAHs) with NO₃/N₂O₅, OH radicals, and O₃
were studied in a laboratory photochemical chamber. Ambient PM[subscript 2.5] and PM₁₀ samples were
collected from Beijing, China and Riverside, California, and exposed under simulated
atmospheric long-range transport conditions...
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& Technology, Texas A&M Health Science Center, Houston,
Texas, USA, 77030; 5College of Urban and Environmental
While fluorochemicals have been detected all over the world and in wastewater
treatment plants, the effect of wastewater effluent on the receiving waters has not been
evaluated. In the first study, the mass flow of fluorochemicals emanating from
wastewater treatment plants along the Glatt River in Switzerland was evaluated. The...
The use of semi-volatile organic compounds (SOCs) as molecular markers to identify the contributions of regional and long-range atmospheric transport, as well as current and historic sources, and contaminant deposition in remote ecosystems of the Western U.S. was investigated. Trans-Pacific air masses influenced by Siberian biomass burning events had elevated...
The heterogeneous reactions of ambient particulate matter (PM)-bound polycyclic
aromatic hydrocarbons (PAHs) and nitro-PAHs (NPAHs) with NO₃/N₂O₅, OH radicals, and O₃
were studied in a laboratory photochemical chamber. Ambient PM[subscript 2.5] and PM₁₀ samples were
collected from Beijing, China and Riverside, California, and exposed under simulated
atmospheric long-range transport conditions...
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., ...
& Simonich, S. L. M. (2014). Heterogeneous Reactions of Particulate
Matter-Bound PAHs and NPAHs with NO₃/N₂O
A healthy nation starts with healthy citizens, and participation in sports is one of the most powerful ways to promote healthy habits for a lifetime—not only for physical fitness but also for emotional wellbeing and social cohesion. The natural enthusiasm that children and adolescents (collectively referred to as “youth”) have...
Polycyclic aromatic hydrocarbons (PAHs) with a molecular weight (MW) of 302
and oxygenated-PAHs (OPAHs) have demonstrated toxicity beyond that of
frequently monitored and known carcinogenic PAHs. Airborne particulate matter
(PM) was characterized for MW 302 isomers to evaluate risk and air quality
indices and OPAHs in order to fill data...
We are witnessing the rise of the data-driven science paradigm, in which massive amounts of data - much of it collected as a side-effect of ordinary human activity - can be analyzed to make sense of the data and to make useful predictions. To fully realize the promise of this...
The purpose of the study was to learn more about the ways in which caregivers perceive the effects of adult day services. The goal was to help inform adult day providers about services family caregivers find useful. An ecological model was used as a framework. Data were collected from focus...
Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous contaminants and are mostly products of the incomplete combustion of organic material. PAHs are often found in environmental samples as a complex mixture of isomers. In addition, the same sources that produce complex PAH mixtures also produce other poorly characterized mixtures of organic compounds,...
Analysis of observations on sequential events over time is common in real life. Sequential measurements over time describing the behavior of systems are usually called time series data, which have been collected in a wide range of disciplines. Over the years there have been multiple research areas in studying stochastic...
Histone deacetylase (HDAC) inhibitors have the potential to de-repress epigenetically silenced genes in cancer cells, leading to cell cycle arrest and apoptosis. Dietary HDAC inhibitors derived from natural phytochemicals are promising anticancer agents. In this thesis, metabolites from natural organosulfur and organoselenium compounds, i.e. allyl mercaptan (AM), β-methylselenopyruvate (MSP) and...
In recent decades, there has been increased attention on human exposure to, and subsequently toxicity of, Polycyclic Aromatic Hydrocarbons (PAHs). PAHs are widespread organic pollutants and some have been shown to be toxic, carcinogenic and mutagenic. This research was focused on understanding the link between global PAH emissions and lung...
Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
The objective of this research was to assess the variability of POP deposition by snow on a 10 km spatial scale by measuring the POP concentrations in fresh-fallen snow from remote alpine sites. Samples of pre-metamorphic snow were concurrently collected from three remote alpine sites, of matched altitude and exposure,...
Prostate cancer is the second leading cause of cancer related death in American men. Epidemiologic studies suggest that cruciferous vegetable intake may lower the risk for many cancers, including prostate and colon. Isothiocyanates (ITC) are phytochemicals derived from cruciferous vegetables such as broccoli, Brussels sprouts, cauliflower, and cabbage that may...
Polycyclic aromatic hydrocarbons (PAHs) are a group of environmental contaminants consisting of fused benzene rings. Parent-PAHs, methylated-PAHs (MPAHs), and PAHs with molecular weight of 302 a.m.u (MW302-PAHs) are considered as unsubstituted-PAHs. These unsubstituted-PAHs undergo transformation reactions resulting in the formation of PAH-transformation products (PAH-TPs), or substituted-PAHs, including nitrated-, oxygenated-, and...
Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...
The purpose of this research was to compare four different media that were used to monitor SOC atmospheric concentrations in remote ecosystems. The accumulation of semi-volatile organic compounds, including pesticides, polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs), was investigated in lichen, 2-year old conifer needles, resin-based passive air sampling...