Background:
In the SOD1^G93A mutant rat model of amyotrophic lateral sclerosis (ALS), neuronal death and rapid paralysis progression are associated with the emergence of activated aberrant glial cells that proliferate in the degenerating spinal cord. Whether pharmacological downregulation of such aberrant glial cells will decrease motor neuron death and prolong...
A novel approach for the colorimetric detection of creatinine in a paper/polycaprolactone hybrid microfluidic device using alkaline3,5-dinitrobenzoate (DNB) is described. The reaction parameters of reagent concentration, alkalinity, and analysis time are optimized for fast reaction times and high color yield. Microfluidic devices incorporating this assay are designed and fabricated to...
In the future, Earth will be warmer, precipitation events will be more extreme, global mean sea level will rise, and many arid and semiarid regions will be drier. Human modifications of landscapes will also occur at an accelerated rate as developed areas increase in size and population density. We now...
The last glacial period exhibited abrupt Dansgaard–Oeschger climatic oscillations, evidence of which is preserved in a variety of Northern Hemisphere palaeoclimate archives¹. Ice cores show that Antarctica cooled during the warm phases of the Greenland Dansgaard–Oeschger cycle and vice versa[superscript 2,3], suggesting an interhemispheric redistribution of heat through a mechanism...
Opinions about public lands and the actions of private non-industrial forest owners in the
western United States play important roles in forested landscape management as both public
and private forests face increasing risks from large wildfires, pests and disease. This
work presents the responses from two surveys, a random-sample telephone...
•Plant population genomics informs evolutionary biology, breeding, conservation and bioenergy feedstock development. For example, the detection of reliable phenotype–genotype associations and molecular signatures of selection requires a detailed knowledge about genome-wide patterns of allele frequency variation, linkage disequilibrium and recombination.
•We resequenced 16 genomes of the model tree Populus trichocarpa...
Wood is a major pool of organic carbon that is highly resistant to decay, owing largely to the presence of lignin. The only organisms capable of substantial lignin decay are white rot fungi in the Agaricomycetes, which also contains non–lignin-degrading brown rot and ectomycorrhizal species. Comparative analyses of 31 fungal...
Greenhouse studies were conducted to evaluate the influence of selected adjuvants on
glyphosate efficacy on yellow nutsedge and tuber production. Glyphosate was applied
at 0, 0.25, 0.43, 0.87, 1.26 (1x rate), and 1.74 kg ae ha⁻¹ 31 d after yellow nutsedge
was planted. Each rate was mixed with one of...
Of the major players in the birth and growth of nuclear technology, France and the United States are two of the biggest. Their glaring differences in culture and political regimes, therefore, have resulted in two very different attitudes toward adoption and implementation of nuclear power. Through extensive literary research, cultural...
Of the major players in the birth and growth of nuclear technology, France and the United States are two of the biggest. Their glaring differences in culture and political regimes, therefore, have resulted in two very different attitudes toward adoption and implementation of nuclear power. Through extensive literary research, cultural...