Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
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,
Kenneth C.Land
12
, Simon Gregory
13
, Ze Yang
14
, William Gottschalk
15
, Wei Tao
16
, Jian
Wang
Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
Full Text:
, Ming Qi4, Lars Bolund3,11, Anatoliy Yashin12,
Kenneth C. Land12, Simon Gregory13, Ze Yang14, William
Rapamycin (Rapa) and dietary restriction (DR) have consistently
been shown to increase lifespan. To investigate whether Rapa
and DR affect similar pathways in mice, we compared the effects
of feeding mice ad libitum (AL), Rapa, DR, or a combination of
Rapa and DR (Rapa + DR) on the transcriptome and...
Rapamycin (Rapa) and dietary restriction (DR) have consistently
been shown to increase lifespan. To investigate whether Rapa
and DR affect similar pathways in mice, we compared the effects
of feeding mice ad libitum (AL), Rapa, DR, or a combination of
Rapa and DR (Rapa + DR) on the transcriptome and...
Full Text:
dietary restriction has a larger
effect on the transcriptome and metabolome of liver
Fok, W. C., Bokov
The annual growth rate for the Corvallis-Benton County
area has traditionally been higher than the growth rate for the
State of Oregon. Corvallis is considered to be one of the most
densely settled communities in the state. Since 1972, Corvallis
has experienced a drastic decline in the number of housing...
Empirical algorithms are developed using high-quality GO-SHIP hydrographic measurements of commonly measured parameters (temperature, salinity, pressure, nitrate, and oxygen) that estimate pH in the Pacific sector of the Southern Ocean. The coefficients of determination, R² , are 0.98 for pH from nitrate (pH^N) and 0.97 for pH from oxygen (pH^Ox)...
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in the Southern Ocean
N. L. Williams1*, L. W. Juranek1, K. S. Johnson2, R. A. Feely3, S. C. Riser4
Empirical algorithms are developed using high-quality GO-SHIP hydrographic measurements of commonly measured parameters (temperature, salinity, pressure, nitrate, and oxygen) that estimate pH in the Pacific sector of the Southern Ocean. The coefficients of determination, R² , are 0.98 for pH from nitrate (pH^N) and 0.97 for pH from oxygen (pH^Ox)...
Full Text:
. Williams1, L. W. Juranek1, K. S. Johnson2, R. A. Feely3, S. C. Riser4, L. D. Talley5, J. L. Russell6,
J. L
Herein, we posit a link between the ecological extinction of wolves in the American West
and the expansion in distribution, increased abundance, and inflated ecological influence
of coyotes. We investigate the hypothesis that the release of this mesopredator from wolf
suppression across much of the American West is affecting, via...