To determine whether extreme endurance exercise induces lipid peroxidation, we studied 14 athletes (5 females: 9 males) during a 50 km ultramarathon (trial 1) and during a sedentary protocol (trial 2) one month later. At dinner the evening before the race (or sedentary trial), subjects consumed vitamin E labeled with...
On behalf of the Linus Pauling Institute, I am pleased to welcome you to this conference and, in particular, to the sessions on the Health Benefits of Seafood Consumption. It is our pleasure to be a co-sponsor of these sessions and I look forward to the presentations by the distinguished...
The Conference Program for IIFET, held July 10-14 in Corvallis, Oregon. Program lists the sessions by date and time and includes the session titles, speakers and paper titles.
Protein disulfide isomerase (PDI), a member of the thioredoxin superfamily, contains two domains with significant sequence homology to the active sites in thioredoxin. PDI facilitates the folding of nascent proteins in the endoplasmic reticulum (ER), binds hormones and Ca²⁺, catalyzes the glutathione dependent reduction of dehydroascorbate, serves as a major...
It has been suggested that cellular damage from oxygen radicals is one of the processes leading to cardio-vascular disease and cancer. Natural antioxidants prevent uncontrolled oxidative reactions by decreasing molecular oxygen levels, scavenging chain-initiating and chain-propagating free radicals, chelating metals, or decomposing peroxides. Beer is rich in antioxidants, derived both...
Oxidative stress is the major driving force behind the aging process and many age-related diseases. However, direct experimental evidence of whether antioxidants, such as ascorbate (AA) and lipoic acid (LA) can slow the progression of aging process and/or reduce risks of developing degenerative disease is largely absent. This suggests a...