Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...
Full Text:
,
Sarah Dovgin
2
, Louis Weiss
11
, Gael Brasseur
14
, Dyann Wirth
6,7
, Michael Kent
9
, Leroy
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...
Full Text:
, Farida Esaa2,
Fatima Alibana-Clouser2, Sarah Dovgin2, Louis Weiss11, Gael Brasseur13, Dyann Wirth6,7
Toxoplasma gondii, the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, and is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. gondii forms cysts in vitro that induce oocysts in...
Full Text:
,
Sarah Dovgin
2
, Louis Weiss
11
, Gael Brasseur
14
, Dyann Wirth
6,7
, Michael Kent
9
, Leroy
Mixia osmundae (Basidiomycota, Pucciniomycotina) represents a monotypic class containing
an unusual fern pathogen with incompletely understood biology. We sequenced and analyzed
the genome of M. osmundae, focusing on genes that may provide some insight into its
mode of pathogenicity and reproductive biology.
Mixia osmundae has the smallest plant pathogenic basidiomycete...
Full Text:
Toome, M., Ohm, R. A., Riley, R. W., James, T. Y., Lazarus, K. L., Henrissat, B.,
Albu, S., Boyd, A