Zinc oxide nanoparticles (ZnO NPs) are widely used in a variety of products, thus understanding their health and environmental impacts is necessary to appropriately manage their risks. To keep pace with the rapid increase in products utilizing engineered ZnO NPs, rapid in silico toxicity test methods based on knowledge of...
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., Son, J., Harper, B., Zhou, Z., & Harper, S. (2015). Influence of surface
chemical properties on the
The integration of rapid assays, large datasets, informatics, and modeling can overcome current barriers in understanding nanomaterial structure–toxicity relationships by providing a weight-of-the-evidence mechanism to generate hazard rankings for nanomaterials. Here, we present the use of a rapid, low-cost assay to perform screening-level toxicity evaluations of nanomaterials in vivo. Calculated...
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, pp 666–669
Harper S, Usenko C, Hutchison JE, Maddux BLS, Tanguay RL
(2008a) In vivo biodistribution
Inherent nanomaterial characteristics, composition,
surface chemistry, and primary particle size,
are known to impact particle stability, uptake, and
toxicity. Nanocomposites challenge our ability to predict
nanoparticle reactivity in biological systems if they
are composed of materials with contrasting relative
toxicities. We hypothesized that toxicity would be
dominated by the nanoparticle...
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nanoparticles
Bonventre, J. A., Pryor, J. B., Harper, B. J., & Harper, S. L. (2014). The impact of
aminated
Zinc oxide nanoparticles (ZnO NPs) are widely used in a variety of products, thus understanding their health and environmental impacts is necessary to appropriately manage their risks. To keep pace with the rapid increase in products utilizing engineered ZnO NPs, rapid in silico toxicity test methods based on knowledge of...
Full Text:
data
composition Size dose(ppm) M(24hpf) DP SM N M(120hpf) Y A E Sn J O H B So PF CF P C T SB TR M
Zinc oxide nanoparticles (ZnO NPs) are widely used in a variety of products, thus understanding their health and environmental impacts is necessary to appropriately manage their risks. To keep pace with the rapid increase in products utilizing engineered ZnO NPs, rapid in silico toxicity test methods based on knowledge of...
Full Text:
CF P C T SB TR
nbi_085:
Aldrich ZnO+Oleic Acid (TLAD25A) 62 0 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0
Strong self-regulation in early childhood is a key predictor of academic and social success from elementary school through college (McClelland et al., 2012). This study analyzed the influence of the age of the child’s parent on the child’s self-regulation as measured by the HTKS (Head-Toes-Knees-Shoulders) measure. Relations between children’s self-regulation...
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. Harper, Megan M. McClelland, Ph.D.
Oregon State University
COLLEGE OF PUBLIC HEALTH AND HUMAN SCIENCES
Strong self-regulation in early childhood is a key predictor of academic and social success from elementary school through college (McClelland et al., 2012). This study analyzed the influence of the age of the child’s parent on the child’s self-regulation as measured by the HTKS (Head-Toes-Knees-Shoulders) measure. Relations between children’s self-regulation...
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Children?
Kevin G. Harper, Megan M. McClelland, Ph.D.
Oregon State University
COLLEGE OF PUBLIC HEALTH AND
Gold nanoparticles (AuNPs) are increasingly used in biomedical applications,
hence understanding the processes that affect their biocompatibility and stability are of
significant interest. In this study, we assessed the stability of peptide-capped AuNPs and
used the embryonic zebrafish (Danio rerio) as a vertebrate system to investigate the impact
of synthesis...
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-Met2-U2; and (c) GSH-His2-U2.
Scale bar = 20 nm; (d) Hydrodynamic diameters of AuNPs with (A) GSH, (B
Gold nanoparticles (AuNPs) are increasingly used in biomedical applications,
hence understanding the processes that affect their biocompatibility and stability are of
significant interest. In this study, we assessed the stability of peptide-capped AuNPs and
used the embryonic zebrafish (Danio rerio) as a vertebrate system to investigate the impact
of synthesis...
Full Text:
Synthesis Method on the Toxicity of
Glutathione-Coated Gold Nanoparticles
Harper, B., Sinche, F., Wu, R. H
Plastids are actively involved in numerous plant processes critical to growth, development and adaptation. They play a
primary role in photosynthesis, pigment and monoterpene synthesis, gravity sensing, starch and fatty acid synthesis, as well
as oil, and protein storage. We applied two complementary methods to analyze the recently published apple...
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of
Sequenced Higher Plant Genomes
Schaeffer, S., Harper, A., Raja, R., Jaiswal, P., Dhingra, A