Persistent and uncontrolled inflammation is the root cause of various debilitating diseases. Given that interleukin-1 receptor–associated kinase 4 (IRAK4) is a critical modulator of inflammation, inhibition of its activity with selective drug molecules (IRAK4 inhibitors) represents a promising therapeutic strategy for inflammatory disorders. To exploit the full potential of this...
Genetic code expansion is a technology that allows for site-specific incorporation of noncanonical amino acids into recombinant proteins at amber stop codons using engineered translational machinery. The technology allows for expanded study into proteins, derived from the integration of novel chemical functions found in noncanonical amino acids, such as fluorescence,...
Boreal and temperate biomes host nearly half of the earth’s forested ecosystems. The temperate rainforests of the Pacific coast of North America constitute nearly half of all temperate rainforests on earth. Along the northern extent of this region, the perhumid and sub-polar rainforests of southeast and southcentral Alaska are among...
Research has shown that more efforts are needed to increase high school completion and postsecondary enrollment among Latino youths. However, little is known regarding efforts that engage both Latino youths and their parents. To address this gap, we surveyed Juntos Oregon participants to examine the school and community context Latino...
In nanoscale materials, the Coulombic interaction between electrons are stronger than in bulk materials. These stronger interactions, caused by confinement and reduced dielectric screening, have interesting consequences for light-matter interactions. In carbon nanotubes (CNTs), strong interactions can enhance the impact ionization process, and thus assist photocurrent generation in CNTs. Conversely,...
Carbon nanotube (CNT) photodiodes have potential to convert light into electrical current with high efficiency. However, previous experiments have revealed photocurrent quantum yield (PCQY) well below 100%. In this work, we show that axial electric field increases the PCQY of CNT photodiodes. In optimal conditions our data suggest PCQY >...