The objectives of this study were to determine the extent of absorption of functionalized
single-wall carbon nanotubes (SWCNTs) across the gut epithelial cells in Daphnia magna.
Several microscopic techniques were utilized, including micro-Raman spectroscopy, high-resolution
transmission electron microscopy (HRTEM) and selective area diffraction (SAD). In an
effort to examine the...
Full Text:
Daphnia magna
Edgington, A. J., Petersen, E. J., Herzing, A. A., Podila, R., Rao, A., & Klaine, S. J
The objectives of this study were to determine the extent of absorption of functionalized
single-wall carbon nanotubes (SWCNTs) across the gut epithelial cells in Daphnia magna.
Several microscopic techniques were utilized, including micro-Raman spectroscopy, high-resolution
transmission electron microscopy (HRTEM) and selective area diffraction (SAD). In an
effort to examine the...
Full Text:
Supplemental figure 1.
Figure 1. (A) TEM image of an unstained FBS OH-SWCNT exposed D. magna section
The objectives of this study were to determine the extent of absorption of functionalized single-wall carbon nanotubes (SWCNTs) across the gut epithelial cells in Daphnia magna. Several microscopic techniques were utilized, including micro-Raman spectroscopy, high-resolution transmission electron microscopy (HRTEM) and selective area diffraction (SAD). In an effort to examine the...
Pactamycin, a complex aminocyclitol compound produced by Streptomyces pactum, has significant antibiotic, antitumor, and antiplasmodial activity. However, this natural product has not been developed for clinical use due to its high cytotoxicity. Modulation of its biological properties by chemical synthesis has been difficult due to its complex chemical structure. Therefore,...
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Biosynthesis
Andrew Osborn
Research Mentors: Dr. Taifo Mahmud, Dr. Kerry McPhail
A Bioresource
Pactamycin, a complex aminocyclitol compound produced by Streptomyces pactum, has significant antibiotic, antitumor, and antiplasmodial activity. However, this natural product has not been developed for clinical use due to its high cytotoxicity. Modulation of its biological properties by chemical synthesis has been difficult due to its complex chemical structure. Therefore,...
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By
Andrew Osborn
An Undergraduate Thesis Submitted to
Oregon State University
Chitosan based hemorrhage control dressings provide effective external hemorrhage control while having few side effects. Known residual contaminants present in chitosan formulations include endotoxins and proteins known to stimulate gene expression in the liver. This study investigated gene expression in the liver using rat bio-compatibility models to gain knowledge regarding...
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Based Hemostatic Control Patch in Rat Models
By
Andrew J. Colburn
A thesis submitted to
Oregon
Chitosan based hemorrhage control dressings provide effective external hemorrhage control while having few side effects. Known residual contaminants present in chitosan formulations include endotoxins and proteins known to stimulate gene expression in the liver. This study investigated gene expression in the liver using rat bio-compatibility models to gain knowledge regarding...
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Subcutaneous Chitosan Patch Formulations
Andrew Colburn1, Leslie Dyal, Ph.D.2 and John Mata Ph.D.2
Oregon
High Temperature Gas Reactors (HTGRs) are positioned to disrupt local and global markets via their unique ability to produce carbon-free process heat, high efficiency power generation, and passively safe operational features. However, significant impediments still exist to delay deployment of this particular technology, including a lack of experimental data, verified...