This thesis describes an investigation of the natural products chemistry of two fungal species of the genus Tolypocladium. Natural products are small organic molecules that are considered non-essential for cell growth and reproduction, and thus part of secondary metabolism. Chemical profiling of these secondary metabolites using a combination of high-performance...
This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by the Genetics Society of America. The published article can be found at: https://doi.org/10.1534/g3.116.027045
The heritability of resistance to eastern filbert blight, caused by Anisogramma anomala, in European hazelnut (Corylus avellana) was evaluated in the progeny of seven cultivars crossed in 12 combinations. Progeny produced by crossing 'VR6-28' with three susceptible cultivars segregated 1:1 for complete resistance to eastern filbert blight. Histograms of disease...
Beauveria sinensis sp. nov. was isolated from a larva of Geometridae (Lepidoptera) collected from Tiantangzhai, Anhui province, China. It is characterized by elongated ellipsoidal to cylindrical conidia, solitary conidiogenous cells that are cylindrical or with slightly swollen bases, white to pale pink colony in culture, and small mycelial pellets consisting...
Spalting fungi show strong potential as natural colorants on a variety of materials, specifically textiles and wood. Four species of spalting fungi are currently utilized in this manner: Scytalidium cuboideum, which produces a red pigment called draconin red, Scytalidium ganodermophthorum, that produces an unknown yellow pigment, and Chlorociboria aeruginosa and...
A hierarchical series of studies, based mainly on molecular data, was conducted to elucidate the life history of the Douglas-fir Swiss needle cast pathogen Phaeocryptopus gaeumannii at macro- and micro-evolutionary scales. This information was then utilized to design and evaluate molecular diagnostic tools for use in studies on the epidemiology...
Fungi in the genus Tolypocladium are diverse in their host associations, but the predominant ecologies include parasites of the ectomycorrhizal genus Elaphomyces and pathogens of insects. The aim of this dissertation research is to examine the evolution of these fungi and their host associations. To accomplish this several lines of...
Cordyceps is a genus of perithecial ascomycetes. It includes over 400 species
that are pathogens of arthropods and parasites of the truffle genus Elaphomyces. Based
on the morphology of cylindrical asci, thickened ascus apices and filiform ascospores,
it is classified in the Clavicipitaceae (Hypocreales), which also includes endophytes
and epiphytes...
Since the discovery of penicillin in 1928, the fungal kingdom has remained a fertile source for the discovery of new, biologically active, natural products. Further, as natural products continue to be discovered from fungi, a deeper understanding of the critical role of specialized metabolism in fungal ecology is afforded. The...
The ascomycete fungus Tolypocladium inflatum, a pathogen of beetle larvae, is best known as the producer of the immunosuppressant drug cyclosporin. The draft genome of T. inflatum strain NRRL 8044 (ATCC 34921), the isolate from which cyclosporin was first isolated, is presented along with comparative analyses of the biosynthesis of...