Mastitis is a major endemic disease in dairy cows resulting in significant economic losses for the dairy industry. The peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that is able to bind and be activated by natural (e.g., fatty acids) and synthetic (e.g. thiazolidinedione) compounds. PPARγ plays important roles...
Robots have the potential to protect health care workers, provide patient care, and ultimately save lives in infectious disease outbreaks. Nevertheless, infectious disease outbreak scenarios present unique technological and social challenges for robotics. This work explores what robots can and should do in the fight against infectious diseases. We present...
Although the potato (Solanum tuberosum L.) is a global crop, few growing regions rival the high yields of the Columbia Basin of Eastern Oregon and Washington. Two research projects were conducted in Hermiston, OR to contribute to best management practices for the region. The first project evaluated the efficacy of...
Apart from the traditional role of preventing progression from HIV to AIDS, antiretroviral drug therapy (ART) has an additional benefit of substantially reducing infectiousness, making them potentially an important strategy in the fight against HIV. Recent advances in drug therapy have also seen the use of antiretroviral drugs as a...
Intravenous regional limb perfusion (IVRLP) with tiludronate is a commonly used treatment for distal limb orthopedic disease in horses, but doses and protocols are anecdotal. IVRLP exposes articular cartilage within the perfused area to tiludronate, raising concerns about safety of this treatment, as high tiludronate concentrations (≥19mg/L) were harmful for...
Participation in regular physical activity is important for individuals with a mobility disability to decrease risk of chronic disease, improve quality of life, and maintain and improve functional ability. Consequently, there is a need for programs that can facilitate the adoption and maintenance of regular physical activity for adults with...
Propionic acid, live Propionibacterium shermanii, and
Dimethyl Fumarate (DMF) were tested for their stimulatory or
inhibitory efects on yeast, bacteria, and molds. The amount
of propionic acid required for inhibition of molds was
strain specific and equal to or less than that required for
inhibition of the yeasts. Live P....
A high-pressure liquid chromatography method based on
reported literature was developed for the quantitative
analysis of chlorpheniramine, pseudoephedrine,
phenylpropanolamine and acetaminophen in dissolution
fluids and urine. The effects of buffer, pH and different
concentrations of organic solvent in the mobile phase on
chromatographic separation are described in Chapter I.
Dissolution...
The aryl hydrocarbon receptor (AhR) has recently been described as a novel therapeutic target, given the potent suppression of multiple immune-mediated diseases following activation by the prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In the parent-into-F1 graft-versus-host (GVH) model, suppression of the cytotoxic T-lymphocyte (CTL) response is associated with the presence of CD25⁺CTLA-4⁺IL-10⁺Foxp3[superscript...