This paper develops a new model of software maintenance based upon an objective decision rule which determines whether a given software module can be effectively modified, or if it should instead be rewritten. Completely rewriting a module can be expensive, but it can be even more expensive if the module's...
As part of an HHMI funded research project, I showed that overexpression (OE) of actin (ACT2) in Arabidopsis thaliana alters the expression of genes involved in plant immunity. Others have previously shown that knockout (KO) mutants of actin depolymerizing factor 4 are affected in the same gene as ACT2-OE. For...
Full Text:
; a-act2 Knockout
◦ B- act8 Wildtype; b- act8 Knockout
aaBB
act2 KO
X AAbb
act8 KO
AaBb
As part of an HHMI funded research project, I showed that overexpression (OE) of actin (ACT2) in Arabidopsis thaliana alters the expression of genes involved in plant immunity. Others have previously shown that knockout (KO) mutants of actin depolymerizing factor 4 are affected in the same gene as ACT2-OE. For...
Full Text:
- act8 Wildtype; b- act8 Knockout
aaBB
act2 KO
X
AAbb
act8 KO
AaBb
AAbb
AABb
AABB
Aabb
AaBb
AaBB
aabb
Metabolic disorders affect much of the population, and it is widely believed that they have a genetic basis as well as being influenced by dietary factors. Recent studies have revealed an important role for the neil1 gene in the prevention of metabolic diseases. NEIL1 is a DNA Glycosylase that catalyzes...
Full Text:
.
* Denotes p<0.05 by t-test between KO Sucrose and WT Sucrose
# Denotes p<0.05 by t-test between KO Sucrose
Published January 1963. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Non-alcoholic Steatohepatitis (NASH) is an emerging form of liver disease associated with obesity, type II diabetes and dyslipidemia. As the prevalence of these metabolic conditions increases, so too has the occurrence of NASH in all sectors of the population. The pathology of this disease is similar to its alcoholic form,...