A nonlinear model is developed to study the time‐dependent relationship between the alongshore variability of a sandbar, a(t), and alongshore‐averaged sandbar position, xc(t). Sediment transport equations are derived from energetics‐based formulations. A link between this continuous physical representation and a parametric form describing the migration of sandbars of constant shape...
Sandbars are ubiquitous, yet not well understood
beach features that change their position and shape in
response to changing wave conditions. We propose and test
a simple empirical model consisting of two coupled linear
differential equations that represents bar dynamics in terms
of wave forcing and two other state variables:...
Coastal communities throughout the US West Coast and elsewhere are facing the daunting task of preparing for climate change impacts, particularly the hazards from increased flooding and erosion. With sea-level rise, changing storminess patterns, and possible changes to the frequency and severity of major El Niño events, communities are already...
In 2004 the National Toxicology Program published an article describing their intent to pursue toxicology testing and risk assessment practices solely reliant on high throughput in vitro datasets and in silico modeling for dose-response assessments. Support and contributions form regulatory agencies and a significant portion of the life sciences community...
The field of toxicology is challenged with a vast number of environmental chemicals and mixtures to which humans and ecosystems are exposed with limited toxicity data available. Chemical hazard assessment traditionally utilizes mammalian models and can be both cost- and time-limiting and may pose ethical concerns. To rapidly tackle this...
Cytokinesis separates replicated chromosomes and cytoplasm into two
daughter cells. In animal cells, this is achieved by the formation of a cleavage
furrow that bisects the mitotic (or meiotic) spindle. It is known that the mitotic
apparatus defines the cell cleavage plane. However, it is not clear how the mitotic...
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; Matuliene and
Kuriyama, 2002). Yet, whether these interactions are essential in furrow
positioning are
Polycyclic aromatic hydrocarbons (PAHs) are present in the environment as complex mixtures with components that have diverse carcinogenic potencies and mostly unknown interactive effects. Non-additive PAH interactions have been observed in regulation of cytochrome P450 (CYP) gene expression in the CYP1 family. To better understand and predict biological effects of...
Neuromuscular physiology has been extensively investigated
in several groups of vertebrates excluding fish. To
understand the nature of neuromuscular transmission in this
group, the response of the pectoral fin abductor muscle of
black bass (Micropterus salmoides) to nerve stimulation
under the influence of an anticho1inesterase agent was
studied. Diisopropylfluorophosphate (DFP),...