Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome...
Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome...
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Medlock
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, Cheri 4
Goodall
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, Samanthi Wickramasekara
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, Claudia S. Maier
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a
Department
Signal transduction within and between cells is at the core of biological activity in all living systems. Signaling networks are required for regulating biological functions, including growth, development and survival. Deregulation of signaling cascades has been linked to chronic and acute diseases and disorders This thesis focuses on mass spectrometry...
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Abstract approved: ______________________________________________________
Claudia S. Maier
The post-translational modification of proteins by electrophilic oxylipids is emerging as an important mechanism that contributes to the complexity of proteomes. Enzymatic and non-enzymatic oxidation of biological lipids results in the formation of chemically diverse electrophilic carbonyl compounds, such as 2-alkenals and 4-hydroxy alkenals, epoxides and eicosanoids with reactive cyclopentenone...
The post-translational modification of proteins by electrophilic oxylipids is emerging as an important mechanism that contributes to the complexity of proteomes. Enzymatic and non-enzymatic oxidation of biological lipids results in the formation of chemically diverse electrophilic carbonyl compounds, such as 2-alkenals and 4-hydroxy alkenals, epoxides and eicosanoids with reactive cyclopentenone...
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detection and identification
Yury V. Vasil’ev, Shin-Chen Tzeng, Lin Huang and Claudia S. Maier
Diet History Questionnaires (DHQ) can only provide general information about a person’s nutritional intake. It is unable to cluster groups of people based on diets or lifestyles, nor identify specific foods that may play a role in disease prevention. The aim of this study was to validate the use of...
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154 (12): 1089–99.
Stevens, Jan Fredrick., Maier, Claudia S. 2014. "Phytochemistry Reviews-The
Obesity is achieved at the point where fat accumulation begins to exert deleterious effects on an organism. The human body accrues fat when there is an energy imbalance occurring, where caloric intake exceeds expenditure.Many anti-obesity drugs used in the past have had undesirable side effects, and currently there is a...
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Food Res, 52(1), 7-25.
In 2008, Dr.’s Fred Stevens and ClaudiaMaier put out a paper stating that
Pathogenic mycobacteria are important agents causing human disease. Mycobacterium avium subsp. hominissuis
(M. avium) is a species of recalcitrant environmental pathogen. The bacterium forms robust biofilms that allow it to
colonize and persist in austere environments, such as residential and commercial water systems. M. avium is also an
opportunistic pathogen...
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neutrophil survival
McNamara, M., Tzeng, S. C., Maier, C., Wu, M., & Bermudez, L. E. (2013).
Surface
Pathogenic mycobacteria are important agents causing human disease. Mycobacterium avium subsp. hominissuis
(M. avium) is a species of recalcitrant environmental pathogen. The bacterium forms robust biofilms that allow it to
colonize and persist in austere environments, such as residential and commercial water systems. M. avium is also an
opportunistic pathogen...
Background:
Very few closed genomes of the cyanobacteria that commonly produce toxic blooms in lakes and reservoirs are available, limiting our understanding of the properties of these organisms. A new anatoxin-a-producing member of the Nostocaceae, Anabaena sp. WA102, was isolated from a freshwater lake in Washington State, USA, in 2013...