Listeria monocytogenes is the third most deadly foodborne pathogen in the United States. The young and elderly, as well as pregnant and immunocompromised people are the population most susceptible to serious illness and death from listeriosis infections.
Unlike most foodborne pathogens, L. monocytogenes does not live a solely enteric lifestyle....
The utility of the fatty acid biomarker (FAB) approach in fisheries ecology is limited by our understanding of how
biotic and abiotic factors determine dietary markers in fish tissues. An 8-week laboratory experiment was
conducted on two species of juvenile gadids (Pacific cod, Gadus macrocephalus and walleye Pollock, Theragra
chalcogramma)...
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Pacific juvenile gadids: A laboratory feeding study
Louise A. Copeman a,b,⁎, Benjamin J. Laurel c,1
Active-sampling approaches are commonly used for
personal monitoring, but are limited by energy usage and data that may
not represent an individual’s exposure or bioavailable concentrations.
Current passive techniques often involve extensive preparation, or are
developed for only a small number of targeted compounds. In this work,
we present a...
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Personal Monitoring Devices
Steven G. O’Connell, Laurel Kincl, and Kim A. Anderson
Number of pages: 9
Active-sampling approaches are commonly used for
personal monitoring, but are limited by energy usage and data that may
not represent an individual’s exposure or bioavailable concentrations.
Current passive techniques often involve extensive preparation, or are
developed for only a small number of targeted compounds. In this work,
we present a...
Full Text:
Silicone Wristbands as Personal Passive Samplers
O'Connell, S. G., Kincl, L. D., & Anderson, K. A. (2014
Active-sampling approaches are commonly used for
personal monitoring, but are limited by energy usage and data that may
not represent an individual’s exposure or bioavailable concentrations.
Current passive techniques often involve extensive preparation, or are
developed for only a small number of targeted compounds. In this work,
we present a...
Full Text:
body) may be a novel way to examine chemical toxicants in a
manner similar to silicone wristbands
The utility of the fatty acid biomarker (FAB) approach in fisheries ecology is limited by our understanding of how
biotic and abiotic factors determine dietary markers in fish tissues. An 8-week laboratory experiment was
conducted on two species of juvenile gadids (Pacific cod, Gadus macrocephalus and walleye Pollock, Theragra
chalcogramma)...
Full Text:
Supplemental Material 1: Total lipids and lipid classes for flesh of juvenile (a) Pacific cod and 2
(b
Antisense oligonucleotide (AO)-mediated exon-skipping therapeutics shows great promise in correcting frame-disrupting mutations in the DMD gene for Duchenne muscular dystrophy. However, insufficient systemic delivery limits clinical adoption. Previously, we showed that a glucose/fructose mixture augmented AO delivery to muscle in mdx mice. Here, we evaluated if fructose alone could enhance...
Full Text:
Promotes Uptake and Activity of Oligonucleotides With Different Chemistries in a Context-dependent Manner
Antisense oligonucleotide (AO)-mediated exon-skipping therapeutics shows great promise in correcting frame-disrupting mutations in the DMD gene for Duchenne muscular dystrophy. However, insufficient systemic delivery limits clinical adoption. Previously, we showed that a glucose/fructose mixture augmented AO delivery to muscle in mdx mice. Here, we evaluated if fructose alone could enhance...
Full Text:
Supplementary Information
Supplementary Figure 1.
a b
c d
We have recently reported that cell-penetrating peptides (CPPs) and novel chimeric peptides containing CPP (referred as
B peptide) and muscle-targeting peptide (referred as MSP) motifs significantly improve the systemic exon-skipping activity
of morpholino phosphorodiamidate oligomers (PMOs) in dystrophin-deficient mdx mice. In the present study, the general
mechanistic significance of the...
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Exon-skipping Efficiency
Yin, H., Boisguerin, P., Moulton, H. M., Betts, C., Seow, Y., Boutilier, J