Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
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, Atsushi Nakagawa, Haruki
Nakamura, AnthonyNicholls, Marc Nicklaus, Robert T. Nolte, Anil K.
Padyana
Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
Full Text:
Nakamura,28 AnthonyNicholls,15
Marc Nicklaus,29 Robert T. Nolte,30 Anil K. Padyana,31 Catherine E
The thesis area is located in north-central Oregon approximately 20 km west of the town of Mitchell. The rocks exposed in the area belong to the Clarno Formation. This study supports the informal reclassification of the Clarno to Group status, composed of an Upper and Lower Clarno Formation. An angular...
The crawfish enterprise of South Louisiana is shown to haveexpanded as much as 18-fold since the 1950's. It is estimated(1973) that there are about 44,000 acres of managed crawfish ponds.Of the 334 ponds identified and mapped in the thesis, 231 are classedas open ponds, 45 as rice field ponds, and...
In the future, Earth will be warmer, precipitation events will be more extreme, global mean sea level will rise, and many arid and semiarid regions will be drier. Human modifications of landscapes will also occur at an accelerated rate as developed areas increase in size and population density. We now...
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, Nottingham,
UK, 8Department of Civil Engineering, St. Anthony Falls Laboratory, University of Minnesota
This is an integrated assessment across terrestrial, freshwater, and coastal marine realms. It includes the coast range of Oregon and Washington as well as Vancouver Island in British Columbia. The marine portion only includes the coastline and shallow subtidal; the next iteration will include the offshore component.