Certain 2- chioroethyl nitrosoureas have been demonstrated
to be highly specific inactivators of chymotrypsin
in vitro and glutathione reductase, both in vivo and in
isolated rat hepatocytes. The inactivation of glutathione
reductase in isolated hepatocytes resulted in an increased
sensitivity toward an adriamycin induced oxidative
challenge.
Prolonged incubation of 1-(2-chloroethyl)-3-([1-¹⁴...
A foundation for the control of tumors is presented,
based upon the formulation of a realistic, knowledge-based
mathematical model of the interaction between tumor cells
and the immune system. The parametric control variables
relevant to the latest experimental data, e.g., the sigmoidal
dose-response relationship and Michaelis-Menten dynamics,
are also considered....
In two studies we tested the effect of vitamin B-6
(B-6) intake on in vitro lymphocyte, proliferation and IL-2
production in healthy young women. In Study I, 6 women were
fed a constant diet containing 0.84 mg (4.96 μmols) of B-6
for 12 d, and 1.24 mg (7.33 μmols) and...
In introducing the method of electrical images we first consider
the elementary problem of finding the electric field of a single point
charge and an infinite conducting plane. Then a problem involving a
conducting sphere and an exterior point charge is investigated and
the results are applied in the solution...