Natural products have long been an important source of resources for humans. Many of these compounds possess unique chemical structures and potent biological properties. By targeting natural products with specific chemical properties, we can gain a better understanding of the roles these compounds play in the environment and their interactions...
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Supplementary Figure 2.5. Extracted ion chromatograms of fischerellin A (m/z 409.2-409.3
Production of fresh produce takes place outdoors, and therefore, is exposed to many routes of contamination (e.g., soil, contaminated water, manure, etc.) by human pathogens. Although precautions are taken to reduce this risk, pathogens can be regularly introduced to produce handling facilities. To manage the risk of cross-contamination from potentially...
(Polycyclic aromatic hydrocarbons) PAHs are widespread in the environment, and are derived from both natural and anthropogenic sources. The physicochemical properties of PAHs along with the wide range of PAH sources leads to their persistence in the environment. Since PAHs are ubiquitous, and have the potential to illicit adverse effects,...
Gamma Ray Bursts (GRBs) are the most energetic explosions in the Universe, producing up to $\sim10^{53}$ ergs of energy in the first few seconds of their emission -- the so-called prompt phase that is dominated by high energy X-ray and $\gamma$-ray photons. The very large luminosities released in these events...
The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...
Breast cancer is the second most common cancer among women in the US, however, only a small fraction of cases are attributable to heritable genetic mutations; the bulk arises from various behavioral and environmental factors. Loss of functional p53 is observed in over 50% of cases, and its activity relies...
Silicone wristbands are passive sampling devices (PSD) that sequester bioavailable organic chemicals in the environment. In environmental health studies, silicone wristbands are easy to wear and can provide personal exposure data about complex chemical mixtures. This dissertation includes an overview of PSD technology, a literature review of current wristband research...
Silicone wristbands are easy-to-wear passive samplers that have been readily adapted into environmental health studies since first reported in 2014. Wristbands can be worn during normal daily activities and sequester a wide range of bioavailable organic chemicals. This dissertation includes a thorough review of silicone wristband technology, as well as...
As robotic systems become increasingly prevalent in our lives (e.g., by harvesting food, assisting with disaster response and defense, and transporting persons and our goods around the world) there is a growing need to ensure that they can cooperate to achieve their intended goals. Robotic cooperation in the real-world is...
The post-emission total kinetic energy release (TKE) in the neutron induced fission of ²³²Th was measured (using white spectrum neutrons from LANSCE) for neutron energies from En = 3 to 91 MeV. In this energy range the average post-neutron total kinetic energy release decreases from 162.3 ± 0.3 at En...