Modern engineered systems are increasingly integrated into society, decentralized, and interconnected. However, scale and complexity create unique challenges in system design, such as emergent behavior and unintended consequences. This work investigates the structural characteristics of robustness in complex engineered systems by identifying patterns of under-recognized vulnerabilities at various levels of...
Alcohol is a widely consumed, nonessential, bioactive nutrient with end-organ effects on the skeleton. Moderate levels of alcohol consumption are generally associated with increased bone mineral density (BMD), whereas higher intake levels result in reduced bone formation, bone loss, and increased risk for osteoporotic fracture. Given the negative impact of...
Pseudomonas aeruginosa is an opportunistic human pathogen that infects immunocompromised individuals such as those suffering from burns or the genetic disorder cystic fibrosis. This organism utilizes a cell-cell communication mechanism known as quorum sensing (QS) to coordinate virulence gene expression and biofilm formation. It has three interconnected QS systems, namely...
Few remote health monitoring (RHM) studies have included Mexican-origin Latinos, and even fewer have explored RHM acceptance and utility, reasons for RHM uptake success or failure, or how cultural values influence RHM use among this population. The primary purpose of this study was to determine the remote health monitoring (RHM)...
Viruses and other selfish genetic elements are dominant entities in the biosphere, with respect to both physical abundance and genetic diversity. Various selfish elements parasitize on all cellular life forms. The relative abundances of different classes of viruses are dramatically different between prokaryotes and eukaryotes. In prokaryotes, the great majority...
Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
Frost injury is one of the major factors limiting potato production in many parts
of the world. It would be desirable to transfer the frost-tolerance traits from the hardy
relatives to the cultivated potato, however, progress has been very slow. Since Solanum
commersonii has been the major source of frost...
This dissertation investigated potential ecological limitations to seedling regeneration in young, seasonally dry, evergreen forest restoration plantations in northern Thailand. We explored whether recruitment of colonizing tree species in the restoration plantations can be attributed to seed dispersal mode (i.e. abiotic or animal dispersal) and seed size. We did this...
Field and greenhouse experiments were conducted in 1996 and 1997 to evaluate the effects of integrating conservation tillage and cover cropping on broccoli production as well as agroecological parameters. A field experiment was conducted during 1996-97 at the Oregon State University Horticulture Research farm near Corvallis, OR. The specific objectives...