The domestic cat (Felis silvestris catus) has shared an intertwined existence with humans for thousands of years, living on our city streets and in our homes. Yet, little scientific research has focused on the cognition of the domestic cat, especially in comparison to human’s other companion, the domestic dog (Canis...
Knowledge of the mean recharge elevation (MRE) of water resources is
important for informing conservation and protection practices where water security is threatened by population growth, urban expansion, and land and climate changes. In this study a Bayesian approach was developed and applied to determine the MRE of 682 surface...
In Oregon, "Incompetent to Stand Trial (1ST) Patients" were observed to be increasing in number, remaining in the hospital longer, and costing more to treat. A study was designed to investigate variables that could be used to predict their length of stay at Oregon State Hospital. Data for thirteen independent...
Real-time, high efficiency neutron spectroscopy has, historically, been a persistent challenge in the field of radiation detection and, for the most part, has gone unsolved. The most promising method to resolve this challenge, is the boron-capture technique using an organic scintillation system (BC-523a). Detectors that utilize this method possess an...
Understanding the precise role of the immune system in cancer has been hindered by the complexity of the immune response and challenges in measuring immune cell types in health and disease in the context of large epidemiologic studies. In this review, we present the rationale to study immunity in cancer...
Carbon tetrachloride (CT) and chloroform (CF) were transformed in batch reactor experiments conducted with anaerobic dechlorinating cultures and supernatant (ADC+S) harvested from continuous flow reactors. The Evanite (EV-5L) and Victoria/Stanford (VS-5L) cultures capable of respiring trichloroethene (TCE), 1,2-cis-dichloroethene (cDCE), and vinyl chloride (VC) to ethene (ETH) were grown in continuous...
The potent antitumor agent phorboxazole A was synthesized from six subunits comprising C1-C2 (115), C3-C8 (98), C9-C19 (74), C20-C32 (52), C33-C41 (84) and C42-C46 (85). Tetrahydropyrans B and C containing cis-2,6-disubstitution were fabricated via palladium(II)-mediated intramolecular alkoxycarbonylation which, in the case of tetrahydropyran C, was carried out with catalytic palladium(II)...
The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A.
The synthesis used a convergent approach involving...
The stereospecific reagent-controlled homologation (StReCH) of boronic esters with putative lithiooxiranes generated in situ from appropriate precursors via sulfoxide-lithium exchange, tin-lithium exchange, and direct lithiation is described with an emphasis on the first lithiation technique which allows for the regio- and stereo-specific generation of all types of lithiooxirane isomer. Transient...
Full Text:
-defined Lithiated Oxiranes
Abstract approved:
Paul R. Blakemore
The stereospecific reagent
John Archibald Wheeler (09 July 1911- ) is a familiar name to physicists and historians of physics alike. Among his many contributions to the corpus of knowledge, in 1939 John Wheeler and Niels Bohr co-authored the first paper on the generalized mechanism of nuclear fission. Beyond that seminal work, Wheeler...