Index Catalog // ScholarsArchive@OSU

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry: Too big to fail?

Creator:: Hartung, Daniel M., Bourdette, Dennis N., Ahmed, Sharia M., and Whitham, Ruth H.
Abstract:: Objective: To examine the pricing trajectories in the United States of disease-modifying therapies (DMT) for multiple sclerosis (MS) over the last 20 years and assess the influences on rising prices. Methods: We estimated the trend in annual drug costs for 9 DMTs using published drug pricing data from 1993 to...
Resource Type:: Article

Contribution of Calcium Oxalate to Soil-Exchangeable Calcium

Creator:: Dauer, Jenny M. and Perakis, Steven S.
Abstract:: Acid deposition and repeated biomass harvest have decreased soil calcium (Ca) availability in many temperate forests worldwide, yet existing methods for assessing available soil Ca do not fully characterize soil Ca forms. To account for discrepancies in ecosystem Ca budgets, it has been hypothesized that the highly insoluble biomineral Ca...
Resource Type:: Article
Full Text:: Lippincott Williams & Wilkins. Unau 0.1 M NH4OAc controls, one-way ANOVA, P < 0.001; Fig. 1A). Before

A Review of Contemporary Methods for the Presentation of Scientific Uncertainty

Creator:: Makinson, K. A., Hamby, D. M., and Edwards, J. A.
Abstract:: Graphical methods for displaying uncertainty are often the most concise and informative way to communicate abstract concepts. Presentation methods currently in use for the display and interpretation of scientific uncertainty are reviewed. Numerous subjective and objective uncertainty display methods are presented, including qualitative assessments, node and arrow diagrams, standard statistical...
Resource Type:: Article

Evaluation of a Workplace Treadmill Desk Intervention: A Randomized Controlled Trial

Creator:: Schuna, John M., Jr., Swift, Damon L., Hendrick, Chelsea A., Duet, Megan T., Johnson, William D., Martin, Corby K., Church, Timothy S., and Tudor-Locke, Catrine
Abstract:: OBJECTIVE: To evaluate the effectiveness of a 3-month treadmill desk intervention in eliciting changes in physical activity and sedentary behavior among overweight/obese office workers. METHODS: A randomized controlled trial was conducted among overweight/obese office workers (n=41; mean age = 40.1 ± 10.1 years) at a private workplace. Participants were randomly...
Resource Type:: Article
Full Text:: Trial Schuna Jr., J. M., Swift, D. L., Hendrick, C. A., Duet, M. T., Johnson, W. D., Martin, C. K

Effect of β-Blockers on Cardiac and Pulmonary Events and Death in Older Adults With Cardiovascular Disease and Chronic Obstructive Pulmonary Disease

Creator:: Lee, David S. H., Markwardt, Sheila, McAvay, Gail J., Gross, Cary P., Goeres, Leah M., Han, Ling, Peduzzi, Peter, Lin, Haiqun, Dodson, John A., and Tinetti, Mary E.
Abstract:: CONTEXT: In older adults with multiple conditions, medications may not impart the same benefits seen in patients who are younger, or without multi-morbidity. Furthermore, medications given for one condition may adversely affect other outcomes. Beta-blocker (β-Blocker) use with coexisting cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) is such...
Resource Type:: Article

PRex: an experiment to investigate detection of near-field particulate deposition from a simulated underground nuclear weapons test vent

Creator:: Keillor, Martin E., Arrigo, Leah M., Baciak, James E., Chipman, Veraun, Detwiler, Rebecca S., Emer, Dudley F., Kernan, Warnick J., Kirkham, Randy R., MacDougall, Matthew R., Milbrath, Brian D., Rishel, Jeremy P., Seifert, Allen, Seifert, Carolyn E., and Smart, John E.
Abstract:: A radioactive particulate release experiment to produce a near-field ground deposition representative of small-scale venting from an underground nuclear test was conducted to gather data in support of treaty capability development activities. For this experiment, aCO₂‐driven “air cannon” was used to inject ¹⁴⁰La, a radioisotope of lanthanum with 1.7‐d half-life...
Resource Type:: Article

The Effect of Intensive versus Usual Blood Pressure Control on Kidney Function Among Persons With Prior Lacunar Stroke: A Post-Hoc Analysis of the Secondary Prevention of Small Subcortical Strokes (SPS3) Randomized Trial

Creator:: Peralta, Carmen A., McClure, Leslie A., Scherzer, Rebecca, Odden, Michelle C., White, Carole L., Shlipak, Michael, Benavente, Oscar, and Pergola, Pablo
Abstract:: Background—The effect of intensive blood pressure (BP) lowering on kidney function among individuals with established cerebrovascular disease and preserved estimated glomerular filtration rate (eGFR) is not established. Methods and Results—Among 2610 participants randomized to a lower (<130 mm Hg) versus higher (130–149 mm Hg) systolic BP target with repeated measures...
Resource Type:: Article

An Anthropological Approach to Teaching Health Sciences Students Cultural Competency in a Field School Program

Creator:: Hutchins, Frank T., Brown, Lori DiPrete, and Poulsen, Keith P.
Abstract:: International immersion experiences do not, in themselves, provide students with the opportunity to develop cultural competence. However, using an anthropological lens to educate students allows them to learn how to negotiate cultural differences by removing their own cultural filters and seeing events through the eyes of those who are culturally...
Resource Type:: Article
Full Text:: 10.1097/ACM.0000000000000088 Lippincott Williams & Wilkins Accepted Manuscript http

Effect of Protease Inhibitors on Steady-State Pharmacokinetics of Oral Norethindrone Contraception in HIV-Infected Women

Creator:: Atrio, Jessica, Stanczyk, Frank Z., Neely, Michael, Cherala, Ganesh, Kovacs, Andrea, and Mishell, Daniel R., Jr.
Abstract:: OBJECTIVE: Pharmacokinetic interactions exist between combined oral contraceptives and protease inhibitors (PI). However, such information is lacking for progestin-only oral contraception. We sought to define the steady-state pharmacokinetic interaction between norethindrone (NET) and PI in HIV-infected women. METHODS AND DESIGN: We conducted an open-label, prospective, nonrandomized trial to characterize the...
Resource Type:: Article
Full Text:: ., Stanczyk, F. Z., Neely, M., Cherala, G., Kovacs, A., & Mishell Jr, D. R. (2014). Effect of Protease

Prenatal Care in Oregon and Washington: Policy and Utilization for Vulnerable Women

Creator:: Docherty, Angie and Johnston, Alison L.
Abstract:: BACKGROUND: In the prenatal period, women can have sustained contact with nurses and other clinicians, forming relationships that are likely to be health enhancing both for the woman and her unborn child. Yet first trimester care use in Oregon dropped noticeably over the past decade. In comparison with Washington State,...
Resource Type:: Article
Full Text:: /NNR.0000000000000073 Lippincott Williams & Wilkins Accepted Manuscript http

ScholarsArchive@OSU

The cost of multiple sclerosis drugs in the US and the pharmaceutical industry: Too big to fail?

Contribution of Calcium Oxalate to Soil-Exchangeable Calcium

A Review of Contemporary Methods for the Presentation of Scientific Uncertainty

Evaluation of a Workplace Treadmill Desk Intervention: A Randomized Controlled Trial

Effect of β-Blockers on Cardiac and Pulmonary Events and Death in Older Adults With Cardiovascular Disease and Chronic Obstructive Pulmonary Disease

PRex: an experiment to investigate detection of near-field particulate deposition from a simulated underground nuclear weapons test vent

The Effect of Intensive versus Usual Blood Pressure Control on Kidney Function Among Persons With Prior Lacunar Stroke: A Post-Hoc Analysis of the Secondary Prevention of Small Subcortical Strokes (SPS3) Randomized Trial

An Anthropological Approach to Teaching Health Sciences Students Cultural Competency in a Field School Program

Effect of Protease Inhibitors on Steady-State Pharmacokinetics of Oral Norethindrone Contraception in HIV-Infected Women

Prenatal Care in Oregon and Washington: Policy and Utilization for Vulnerable Women

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