The project team surveyed and interviewed forty identified experts within the diverse tsunami community. The survey revealed that this community is a sophisticated user of Internet search engines and tools and is very familiar with existing information. The sites mentioned most frequently as being helpful were those of the National...
End-user programmers, because they are human, make mistakes. However, past research has not considered how visual end-user debugging devices could be designed to ameliorate the effects of mistakes. This paper empirically examines oracle mistakes mistakes users make about which values are right and which are wrong to reveal differences in...
Previous research has revealed gender differences that impact females’ willingness to adopt software features in end users’ programming environments. Since these features have separately been shown to help end users problem solve, it is important to female end users’ productivity that we find ways to make these features more acceptable...
Three approaches toward the core of halichlorine and pinnaic acid are described. The first approach entails a racemic transannular nitrone-olefin [3+2] cycloaddition from nitrone 238. Construction of the nitrone 238 began with aldehyde 241. Another key feature in this route involved a ring-closing metathesis for the formation of a 14-membered...
Authentication protocols play important roles in network security. A variety of authentication protocols ranging from complex public-key cryptosystems to simple password-based authentication schemes have been proposed. However, currently there is no fully secure authentication scheme that can resist all known attacks. When a user authentication is performed over an insecure...
In this thesis, I studied the translation of dengue virus RNA using a luciferase reporter gene system in Vero cells. The dengue reporter mRNA construct, which harbors 5´-terminal viral nts and 3´-terminal nts, could be translated efficiently compared to an alpha globin reporter construct. The 5´-cap structure and 3´-untranslated region...
Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. The nonproteinogenic amino acid capreomycidine is the signature residue found in the tuberactinomycin family of antitubercular peptide antibiotics and an important element of the pharmacophore. Recombinant VioG, a single module peptide synthetase from the viomycin gene cluster cloned...
Forest growth models in the Pacific Northwest are predominantly empirical. Predictions of yield under alternative silvicultural regimes cannot rely completely on field trials; yet empirical growth models are often inadequate for extrapolating untested regimes and genotypes. The limitations of current models include (1) long time-steps (e.g. 5-10 years); (2) insufficient...
The adsorption and elution of the antimicrobial peptide nisin at hydrophobic,
silanized silica surfaces coated with the poly[ethylene oxide]-poly[propylene oxide]-
poly[ethylene oxide] surfactant Pluronic® F108 was measured in situ, with ellipsometry.
While such layers are known to inhibit protein adsorption, nisin was observed to adsorb in
multilayer quantities, to an...
While there are many more species of reptiles in the tropics than in temperate
latitudes, relatively little is known about the natural history of tropical species of
snakes. Even basic information, such as reproductive ecology and behavior, is lacking. Patterns of reproduction in tropical species differ from patterns in temperate...