Index Catalog // ScholarsArchive@OSU

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

Creator:: Rakkanka, Vipaporn
Abstract:: This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...
Resource Type:: Dissertation
Full Text:: Oral Formulations, (3) A Novel Zero Order Release Matrix Tablet. Abstract approved James W This

New product formulations and pharmacokinetics of acetaminophen

Creator:: Borin, Marie T.
Resource Type:: Dissertation
Full Text:: Pharmacokinetics of Acetaminophen Abstract approved: Redacted for privacy Sustained release acetaminophen dosage

Plant and amphibian assemblages in zero-order basins in the Oregon Coast Range

Creator:: Sheridan, Chris D.
Abstract:: We have a poor understanding of the biotic communities in zero-order basins, drainages extending from ridgelines to the initiation of first-order streams. This study describes baseline plant and amphibian composition in unmanaged zero-order basins in the Oregon Coast Range. Specifically, I studied: i) the spatial distribution and diversity of species,...
Resource Type:: Masters Thesis
Full Text:: Assemglages in Zero-Order Basins in the Oregon Coast Range. ) Signature redacted for privacy. Abstract

Formulation of an oral acetylsalicylic acid suspension and pharmacokinetics of parenteral thrombomodulin analogues

Creator:: Piepmeier, Edward H.
Abstract:: Sustained concentrations of active compound were maintained in vitro and in vivo for an oral and a parenteral dosage form respectively. The vehicle of a oral dosage form was modified and the molecular structure of a parenteral dosage form was modified. An oral dosage form was tested in vitro using...
Resource Type:: Dissertation
Full Text:: approximates a zero order release over the first eight hours or longer depending on the amount of time it has

New product formulation and multiple dose pharmacokinetics of acetaminophen

Creator:: Sahajwalla, Chandrahas G.
Abstract:: Four different treatments of acetaminophen were administered to eight healthy volunteers in multiple doses (five doses). Saliva acetaminophen concentration-time profiles were determined. Non-compartmental pharmacokinetic parameters for the first and last dose were calculated and compared to determine whether acetaminophen exhibited linear or dose dependent pharmacokinetics. Dose corrected area under the...
Resource Type:: Dissertation
Full Text:: linearity of kinetics. Acetaminophen is a prime candidate for sustained release dosage forms (chapter II

Development of Hot-melt Pan-coating, Application to Sustained-release Capsules and Tamper Resistant-coating. 2) Formulation of Verapamil HCl and Diltiazem HCl Semisolid Matrix Capsules. 3) Novel Sustained Release Tablet of Glipizide: Compression of Coated Drug Beads, Formulation, Dissolution, and Convolution. 4) Verapamil Sustained Release: New Formulation and Convolution

Creator:: Nguyen, Chien Ngoc
Abstract:: Hot-melt pan-coating, which is a novel coating method and takes 2-3 hours for 300 mg coating weight gain per capsule and tamper-resistant coating, which takes 30 minutes, is much faster than tedious sugar coating and allows greater coating weight gains in shorter times than spray-melt coating. Although hot-melt pan coating...
Resource Type:: Dissertation
Full Text:: approximately zero-order release, and releases drug nearly independent of paddle speeds 50 and 100 rpm. The

Preparing sustained release dosage forms of nifedipine by hot-melt coating method

Creator:: Le, Hang Thi
Abstract:: A nifedipine sustained release dosage form was prepared by using hot-melt batch coating. Substrates are sugar beads, mesh size 30-35. Stearic acid, Acid Triglyceride, and carnauba wax were coating agents used to make single layer coated beads and multiple layer coated beads containing nifedipine. Dissolution of nifedipine from the beads...
Resource Type:: Masters Thesis
Full Text:: change in ratio of waxes to drug release 64 Preparation of coated beads in order to obtain zero- order

Development and evaluation of a sustained release amoxicillin dosage form

Creator:: Ge, Yan, 1962-
Resource Type:: Masters Thesis
Full Text:: ethylcellulose. The formulation with only 0.16% ethylcellulose gave an approximately zero order release over 24

New acetaminophen products : formulation development and bioavailability

Creator:: Mansell, Libbie J.
Abstract:: Development of a novel, useful, orally administered dosage form providing controlled, sustained release of an active ingredient was desired. Film layers of Aquacoat and Eudragit L-30D (commercially available coating materials) were applied to acetaminophen cores. Amount of coating material, number of polymer layers, and order of application were varied. In...
Resource Type:: Dissertation
Full Text:: dosage form providing controlled, sustained release of an active ingredient was desired. Film layers of

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

Creator:: Hossain, Mohammad
Abstract:: Gastrointestinal (GI) transit data were collected using pigs as animal models. Density and size effects of non-disintegrating dosage forms on GI transit were investigated. Total GI transit times range from 2 to 33 days for 22 administrations of these nondisintegrating dosage forms. Pigs are found to not be an appropriate...
Resource Type:: Dissertation
Full Text:: , non-erodible oral release dosage forms. Development of controlled release dosage forms where the

ScholarsArchive@OSU

A novel self-sealing chewable sustained release tablet of acetaminophen ; Development and evaluation of novel itraconazole oral formulations ; A novel zero order release matrix tablet

New product formulations and pharmacokinetics of acetaminophen

Plant and amphibian assemblages in zero-order basins in the Oregon Coast Range

Formulation of an oral acetylsalicylic acid suspension and pharmacokinetics of parenteral thrombomodulin analogues

New product formulation and multiple dose pharmacokinetics of acetaminophen

Preparing sustained release dosage forms of nifedipine by hot-melt coating method

Development and evaluation of a sustained release amoxicillin dosage form

New acetaminophen products : formulation development and bioavailability

Evaluation of gastrointestinal transit time and novel oral acetaminophen product formulation

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