The construction industry is increasingly adopting off-site and modular construction methods due to the advantages offered in terms of safety, quality, and productivity for construction projects. Despite the advantages promised by this method of construction, modular construction factories still rely on manually-intensive work, which can lead to highly variable cycle...
The high level of parallelism in throughput processors such as GPGPUs has resulted in significantly changed on-chip data traffic behaviors. This demands new research to identify and address the limiting factors of networks-on-chip (NoCs) in the context of throughput processors. In this work, we first quantitatively analyze the performance of...
Genetic factors such as decreased genetic
diversity and increased homozygosity can have detrimental
effects on rare species, and may ultimately limit potential
adaptation and exacerbate population declines. The Gulf
and Atlantic Coastal Plain physiographic region has the
second highest level of endemism in the continental USA,
but habitat fragmentation and...
The production of fuel ethanol from lignocellulosic biomass has the potential to replace a significant portion of non-renewable transport fuels. Woody feedstocks are composed of cellulose, hemicellulose, and lignin. Glucose, the monomer of cellulose, is readily utilized by wild-type S. cerevisiae, but xylose, which comprises 60% of the sugar in...
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2.4.1!–!Identification!of!Xylulokinase!(XK)!as!Xylulose!Utilization!Bottleneck!in!Wild!
Type
A combination of batch fermentations and genome scale flux balance analysis were used to identify and quantify the rate limiting reactions in the xylulose transport and utilization pathway. Xylulose phosphorylation by xylulokinase was identified as limiting in wild type Saccharomyces cerevisiae, but transport became limiting when xylulokinase was upregulated. Further...
The Hawaiian Archipelago is a biologically diverse environment with dynamic interactions between human and biological populations. Political, social, and scientific communities are placing importance on sustainable management of fisheries resources throughout the islands. Many economically important bottomfish in Hawaii have declined in population size due to anthropogenic and environmental pressures....
The economically viable production of value added fuels and chemicals from lignocellulosic feedstocks hinges on our ability to quickly and efficiently transform structural carbon molecules to end products. The sugars in lignocellulosic biomass are held primarily within cellulose and hemicellulose. Cellulose is composed primarily of glucose monomers which are quickly...
Modular construction is increasingly seen as an efficient construction method in terms of time, cost, and energy. The full realization of these advantages partly relies on the efficiency of the production process inside the modular factories, which currently rely on tedious manual monitoring methods or expensive automated techniques. As a...
The counterflow pipeline concept was originated by Sproull et. al.[1] to demonstrate the concept of asynchronous circuits. The basic premise is that a simple architecture with only local communication and control and a simple regular structure will result in increased performance. This thesis attempts to analyze the performance of the...
Cellular Manufacturing Systems (CMS) have provided
significant increase in manufacturing productivity over the
last two decades. This has been achieved because CMS can
overcome the problems due to frequent setups, high in-process
inventories, long throughput times and complex
planning and coordination commonly associated with a batch-type
manufacturing operation. The underlying...