Non-steroidal anti-inflammatory drugs (NSAIDs) are used to control pain and inflammation, but can have serious adverse effects, including gastrointestinal ulceration. Non-selective NSAIDs inhibit both cyclooxygenase isoforms: COX-1 and COX-2. COX-2 is primarily responsible for the inflammatory response, while COX-1 is constitutively expressed, representing the dominant source of prostaglandins for gastric...
urinary eicosanoids, urinary 15F[subscript2t]-isoprostane (lipid peroxidation marker) and hematological/biochemical changes in plasma. Fifteen adult dogs had blood and urine samples obtained prior to, immediately and 4-hours following an agility exercise.
Results: Hematocrit, red blood cells (RBC), albumin, and hemoglobin increased following exercise, with greatest increases correlating to increased skill group...
The purpose of this study was to investigate whether
the beneficial effects which the consumption of fish oil
imparts on hemostatic function can be modified by the level
of dietary selenium. Male Sprague Dawley rats were fed for
eight weeks semipurified diets containing 7% corn oil (by
weight) or 5.5%...
Epidemiological studies have suggested that the consumption
of fish may reduce the risk of cardiovascular disease.
Compared to the number of studies using fish oils, few
studies have used fish itself. Those which have used fish
have generally used fattier fish such as mackerel and salmon
as part of an...
Three experiments were conducted in broiler hens to study the influence of dietary n-3 polyunsaturated fatty acids (PUFA) on egg quality, antioxidant status in progeny, and eicosanoid production in tissue. The objective of experiment 1 was to determine the effect of hen age and dietary n-3 PUFA on egg quality...
The evidence for a protective role of omega
3 fatty acids in CHD is becoming clearer and firmer,
especially for secondary prevention. Intakes of
approximately 800-1,000 mg per day appear to be a prudent
approach for the latter group of patients. The safety of
intakes of up to 3,000 mg...
Egg fat is of considerable importance in the nutrition of the developing chick as a source of energy and essential fatty acids such as linoleic (18:2 n-6) and α-linolenic (18:3 n-3) acids. During incubation, yolk lipids provide fatty acids that are utilized for energy, synthesis of polyunsaturated fatty acids (PUFA)-rich...
Oxylipins are a class of bioactive lipid metabolites derived from polyunsaturated fatty acids (PUFAs) via enzymatic and non-enzymatic pathways. In order to elucidate their overall biological effects, the knowledge of the entire oxylipin profile is needed as oxylipins can have similar or opposing effects in regard to inflammatory events. Their...
Modern strains of broiler chickens are selected for fast growth and are marketed anywhere from 36 to 49 days after a 21-day incubational period. For a viable healthy chick, all the necessary nutrients required for growth and development must be provided by the hen through the fertilized egg. The current...
During the 21 day incubation period, the fertile egg provides nutrients such as fatty acids for energy and polyunsaturated fatty acids (PUFA) for membrane synthesis to the developing chick. The hypothesis tested in the present study is that the type of PUFA fed to the breeder hen can alter tissue...