Index Catalog // ScholarsArchive@OSU

Mass Spectrometry-based Analysis of Superwarfarins and their Metabolites and the Investigation of Novel Treatments for Poisoned Victims

Creator:: Nosal, Daniel Grzegorz
Abstract:: Superwarfarins are anticoagulant rodenticides that are 100 times more potent and 15 times more persistent than warfarin. They have been used since the 1980s and cause over 10,000 cases of accidental and intentional poisonings per year. Apart from inducing uncontrollable bleeding, by inhibiting the vitamin K cycle, superwarfarins can disrupt...
Resource Type:: Dissertation
Full Text:: , Chicago, IL 60612, USA J. AOAC. Int., 2020, 103(3), 770 – 778 DOI: 10.1093/jaoacint

Are Children With Birth Defects at Higher Risk of Childhood Cancers?

Creator:: Carozza, Susan E., Langlois, Peter H., Miller, Eric A., and Canfield, Mark
Abstract:: Birth defects may influence the risk of childhood cancer development through a variety of mechanisms. The rarity of both birth defects and childhood cancers makes it challenging to study these associations, particularly for the very rare instances of each. To address this limitation, the authors conducted a record linkage-based cohort...
Resource Type:: Article
Full Text:: birth defects and specific cancers, particularly for the very Vol. 175, No. 12 DOI: 10.1093/aje/kwr470

ASRP: the Arabidopsis Small RNA Project Database

Creator:: Gustafson, Adam M., Allen, Edwards, Givan, Scott, Smith, Daniel, Carrington, James C., and Kasschau, Kristin D.
Abstract:: ABSTRACT Eukaryotes produce functionally diverse classes of small RNAs (20–25 nt). These include microRNAs (miRNAs), which act as regulatory factors during growth and development, and short-interfering RNAs (siRNAs), which function in several epigenetic and post-transcriptional silencing systems. The Arabidopsis Small RNA Project (ASRP) seeks to characterize and functionally analyze the...
Resource Type:: Article
Full Text:: , Database issue D637–D640 doi:10.1093/nar/gki127 composed of web pages delivered by an apache HTTP

SEK: sparsity exploiting k-mer-based estimation of bacterial community composition

Creator:: Chatterjee, Saikat, Koslicki, David, Dong, Siyuan, Innocenti, Nicholas, Cheng, Lu, Lan, Yueheng, Vehkaperä, Mikko, Skoglund, Mikael, Rasmussen, Lars, K., Aurell, Erik, and Corander, Jukka
Abstract:: MOTIVATION: Estimation of bacterial community composition from a high-throughput sequenced sample is an important task in metagenomics applications. Since the sample sequence data typically harbors reads of variable lengths and different levels of biological and technical noise, accurate statistical analysis of such data is challenging. Currently popular estimation methods are...
Resource Type:: Article
Full Text:: . Bioinformatics, 30(17), 2423-2431. doi:10.1093/bioinformatics/btu320 10.1093/bioinformatics/btu320 Oxford

Social segregation of humpback whales in contrasted coastal and oceanic breeding habitats

Creator:: Derville, Solène, Garrigue, Claire, and Torres, Leigh G.
Abstract:: Article available for download at publisher's website: https://doi.org/10.1093/jmammal/gyx185
Resource Type:: Article

Gene-silencing antisense oligomers inhibit Acinetobacter growth in vitro and in vivo

Creator:: Geller, Bruce L., Marshall-Batty, Kimberly, Schnell, Frederick J., McKnight, Mattie M., Iversen, Patrick L., and Greenberg, David E.
Abstract:: Background: Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA/RNA analogs that silence expression of specific genes. We studied whether PPMOs targeted to essential genes in Acinetobacter lwoffii and A. baumannii are active in vitro and in vivo. Methods: PPMOs were evaluated in vitro using MIC and viability assays, and in...
Resource Type:: Article

Krill biomass and aggregation structure in relation to tidal cycle in a penguin foraging region off the Western Antarctic Peninsula

Creator:: Bernard, Kim S. and Steinberg, Deborah K.
Abstract:: Antarctic krill are a key component of the diet of Adélie penguins inhabiting the Western Antarctic Peninsula (WAP), yet our understanding of the variability of krill distribution patterns within nearshore penguin feeding grounds is limited. A recent study of the foraging patterns of penguins breeding in the northern WAP suggests...
Resource Type:: Article

Variants of Asthma and Chronic Obstructive Pulmonary Disease Genes and Lung Function Decline in Aging

Creator:: Poon, Audrey H., Houseman, E. Andres, Ryan, Louise, Sparrow, David, Vokonas, Pantel S., and Litonjua, Augusto A.
Abstract:: BACKGROUND: A substantial proportion of the general population has low lung function, and lung function is known to decrease as we age. Low lung function is a feature of several pulmonary disorders, such as uncontrolled asthma and chronic obstructive pulmonary disease (COPD). The objective of this study is to investigate...
Resource Type:: Article
Full Text:: Medical Sciences, 69(7), 907-913. doi:10.1093/gerona/glt179 10.1093/gerona/glt179 Oxford University

Advanced Morphological — Behavioral Test Platform Reveals Neurodevelopmental Defects in Embryonic Zebrafish Exposed to Comprehensive Suite of Halogenated and Organophosphate Flame Retardants

Creator:: Noyes, Pamela D., Haggard, Derik E., Gonnerman, Greg D., and Tanguay, Robert L.
Abstract:: Sharp increases in the use of flammable plastics and electronic devices coupled with stricter fire safety requirements have promoted the heavy use of flame retardant chemicals. While flame retardant use has increased, a great deal of uncertainty surrounds their safety with some evidence showing toxicity and risk to human and...
Resource Type:: Article

Modeling spatial effects of PM₂.₅ on term low birth weight in Los Angeles County

Creator:: Coker, Eric, Ghosh, Jokay, Jerrett, Michael, Gomez-Rubio, Virgilio, Beckerman, Bernardo, Cockburn, Myles, Liverani, Silvia, Su, Jason, Li, Arthur, Kile, Molly L., Ritz, Beate, and Molitor, John
Abstract:: Air pollution epidemiological studies suggest that elevated exposure to fine particulate matter (PM₂.₅) is associated with higher prevalence of term low birth weight (TLBW). Previous studies have generally assumed the exposure–response of PM₂.₅ on TLBW to be the same throughout a large geographical area. Health effects related to PM₂.₅ exposures,...
Resource Type:: Article

ScholarsArchive@OSU

Mass Spectrometry-based Analysis of Superwarfarins and their Metabolites and the Investigation of Novel Treatments for Poisoned Victims

Are Children With Birth Defects at Higher Risk of Childhood Cancers?

ASRP: the Arabidopsis Small RNA Project Database

SEK: sparsity exploiting k-mer-based estimation of bacterial community composition

Social segregation of humpback whales in contrasted coastal and oceanic breeding habitats

Gene-silencing antisense oligomers inhibit Acinetobacter growth in vitro and in vivo

Krill biomass and aggregation structure in relation to tidal cycle in a penguin foraging region off the Western Antarctic Peninsula

Variants of Asthma and Chronic Obstructive Pulmonary Disease Genes and Lung Function Decline in Aging

Advanced Morphological — Behavioral Test Platform Reveals Neurodevelopmental Defects in Embryonic Zebrafish Exposed to Comprehensive Suite of Halogenated and Organophosphate Flame Retardants

Modeling spatial effects of PM₂.₅ on term low birth weight in Los Angeles County

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