The large population of 2r>100m near earth objects (NEOs) presents a certain hazard to life on earth. It has been proposed that a nuclear device may be used to alter the course of such objects, thereby averting a catastrophic collision with the earth. The asteroid interdiction problem includes a number...
Epidermal morphogenesis results from a delicate balance between keratinocyte proliferation and differentiation, and this balance is perturbed upon deletion of transcription factor Ctip2. Here we demonstrate that Ctip2, in a cell autonomous manner, controls keratinocyte proliferation and cytoskeletal organization, and regulates the onset and maintenance of differentiation in keratinocytes in...
Background: Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal differentiation, as well as altered lipid composition during development. However, little is known about the role of Ctip2...
Satellite along-track sea surface height (SSH) and multisatellite sea surface temperature (SST) maps are assimilated in a coastal ocean circulation model off Oregon. The study period is June–October 2005, featuring intensive separation of the coastal upwelling jets in the eddy-dominated coastal transition zone (CTZ). The data assimilation (DA) system combines...
Previous work has shown that the Oregon shelf is a sink for atmospheric carbon dioxide (CO₂) during the upwelling season; however, until now, summertime variability in CO₂ exchange and sign of the flux for the rest of the year were unknown. Observations of the partial pressure of CO₂ (pCO₂) in...
The nearly completed U.S. West Coast (USWC) high-frequency radar (HFR) network provides an unprecedented capability to monitor and understand coastal ocean dynamics and phenomenology through hourly surface current measurements at up to 1 km resolution. The dynamics of the surface currents off the USWC are governed by tides, winds, Coriolis...
Connectivity and larval dispersal is explored off the Oregon coast during the summer upwelling season of 2001 using numerical ocean circulation simulations. The study region, with strong wind-driven currents and variable topography, is modeled using the Regional Ocean Modeling System (ROMS) forced by the Coupled Ocean Atmosphere Mesoscale Prediction System....
Correction
10 Aug 2012: Klinck H, Mellinger DK, Klinck K, Bogue NM, Luby JC, et al. (2012) Correction: Near-Real-Time Acoustic Monitoring of Beaked Whales and Other Cetaceans Using a Seaglider™. PLOS ONE 7(8): 10.1371/annotation/57ad0b82-87c4-472d-b90b-b9c6f84947f8.
Prior to cell cleavage, cytokinetic proteins are recruited into the nascent actomyosin contractile ring. Interactions between spindle microtubules and the cell cortex play a critical role in this recruitment. However, direct evidence for physical interaction between microtubules and the cortex has been lacking. Here we reveal the physical connection between...