Effective separation of lanthanides (Ln) from the minor actinides (MA) is a crucial technical challenge to closing the nuclear fuel cycle. This separation is a necessary prerequisite to transmute long-lived isotopes of Am and Cm, which will allow a reduction of the repository volume, thermal load, and radiological toxicity of...
BACKGROUND: Arsenic is an epigenetic toxicant and could influence fetal developmental programming.
OBJECTIVES: We evaluated the association between arsenic exposure and DNA methylation in maternal and umbilical cord leukocytes.
METHODS: Drinking-water and urine samples were collected when women were at <= 28 weeks gestation; the samples were analyzed for arsenic...
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral
outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the
fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly.
Objectives: We examined potential associations between prenatal Hg exposure assessed...
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Environ Health Perspect
doi: 10.1289/ehp.1408561
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Partitioning of trivalent actinides (in particular, americium and curium) from the
fission produced light lanthanides is a major concern of used nuclear fuel reprocessing for
the purposes of waste disposal. Several solvent extraction processes have been developed
to address these chemically difficult separations. The historically employed TALSPEAK
Process utilizes di-2-ethylhexyl...
Air pollution epidemiological studies suggest that elevated exposure to fine particulate matter (PM₂.₅) is associated with higher prevalence of term low birth weight (TLBW). Previous studies have generally assumed the exposure–response of PM₂.₅ on TLBW to be the same throughout a large geographical area. Health effects related to PM₂.₅ exposures,...
Background: Few studies examining the associations between long-term exposure to ambient air pollution and mortality have considered multiple pollutants when assessing changes in exposure due to residential mobility during follow-up.
Objective: We investigated associations between cause-specific mortality and ambient concentrations of fine particulate matter (≤ 2.5 μm; PM₂.₅), ozone (O₃),...
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Environment Cohort (CanCHEC). Environmental Health Perspectives,
123(11), 1180-1186. doi:10.1289/ehp.1409276
Background: There is increasing epidemiologic evidence that arsenic exposure in utero, even at low levels found throughout much of the world, is associated with adverse reproductive outcomes and may contribute to long-term health effects. Animal models, in vitro studies, and human cancer data suggest that arsenic may induce epigenetic alterations,...
BACKGROUND: Half the world’s population lives in urban areas. It is therefore important to identify
characteristics of the built environment that are beneficial to human health. Urban greenness
has been associated with improvements in a diverse range of health conditions, including birth
outcomes; however, few studies have attempted to distinguish...
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Perspectives, 122(10), 1095-1102. doi:10.1289/ehp.1308049
10.1289/ehp.1308049
National Institute of
Background: Prenatal mercury (Hg) exposure is associated with adverse child neurobehavioral outcomes. Because Hg can interfere with placental functioning and cross the placenta to target the fetal brain, prenatal Hg exposure can inhibit fetal growth and development directly and indirectly. Objectives: We examined potential associations between prenatal Hg exposure assessed...
Background: Arsenic is an immunotoxicant. Clinical reports observe the reactivation of varicella zoster virus (VZV) in people who have recovered from arsenic poisoning and in patients with acute promyelocytic leukemia that have been treated with arsenic trioxide. Objective: We evaluated the association between arsenic and the seroprevalence of VZV IgG...