A promising formulation of glipizide comprising compression of four-layer coated beads into tablets which has advantages of providing a lag time (~ 2 hours) before drug release, retaining sustained-release characteristics, and providing approximately zero-order drug release, with drug release nearly independent of paddle speeds of 50 and 100 rpm during...
Full Text:
:5) 0 g 1500 396
F2 67.5 g 2.5 g 5 g 7.5 g 7.5 g (100:5) 10 g 1500 440
F3 67.5 g 2.5 g 5 g 7.5