Twelve N, N'-bis(hydroxy- and methoxybenzoyl)ethylenedi-amines and piperazines have been prepared, tested for antifungal
activity, and screened for gross pharmacological activity in mice.
All twelve compounds showed some activity against Candida albicans,
Trichophyton mentagrophytes and Microsporum gypseum but in every
case the activity was less than that of salicylanilide used as...
The 3-substituded indolic enamide moiety has been found in many marine compounds over the past 20 years. These indolic enamides exhibit various biological properties such as cytotoxic, anthelmintic, antimicrobial and HW-inhibitory activities. Among these indolic enamides, some are (E)-enamides, like coscinamide A and coscinamide B, others are (Z)-configuration in their...