Understanding plant gene promoter architecture has long been a challenge due to the lack of relevant large-scale data sets and analysis methods. Here we present a publicly available, large-scale transcription start site (TSS) dataset in plants using a high-resolution method for analysis of 5’ ends of mRNA transcripts. Our dataset...
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4,5,6
, David L. Corcoran
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, Song Li
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, Cara M. Winter
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, Alexa Carda
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,
PhilipN. Benfey
Understanding plant gene promoter architecture has long been a challenge due to the lack of relevant large-scale data sets and analysis methods. Here we present a publicly available, large-scale transcription start site (TSS) dataset in plants using a high-resolution method for analysis of 5’ ends of mRNA transcripts. Our dataset...
Understanding plant gene promoter architecture has long been a challenge due to the lack of relevant large-scale data sets and analysis methods. Here we present a publicly available, large-scale transcription start site (TSS) dataset in plants using a high-resolution method for analysis of 5’ ends of mRNA transcripts. Our dataset...
Childhood tooth decay is a prevalent and concerning public health issue that is often misunderstood or dismissed. In Oregon specifically, over 50% of children have experienced at least one instance of tooth decay and these rates are even higher for marginalized communities such as children living in poverty, children of...
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Philip McFadden
Childhood tooth decay is a prevalent and concerning public health issue that is
Water fluoridation is considered one of the top ten greatest health achievements of the twentieth century due to its effectiveness in reducing the prevalence of dental caries. However, despite extensive research on the subject, there is little information currently available about how the constituents of drinking water affect the uptake...
This is the first study to explore the ability of an enzyme to recognize and repair
spontaneous age-dependent damage to its own sequence. Protein (D-aspartyl/L-isoaspartyl)
carboxyl methyltransferase (PCM) is known to repair damage that arises
from a spontaneous isomerization of aspartyl and asparaginyl residues in other proteins
during aging. As...
Every cell is faced continuously with the task of transducing a vast number of external signals into appropriate intracellular responses. In mammalian cells, membrane bound receptors modulate the production of secondary messenger molecules, such as cyclic AMP (cAMP). Cell signaling through second messengers relies on the diffusion of such second...
Methodologies that detect biologically active substances have important potential applications for medical diagnostics, drug discovery, and chemical and biological anti-terrorism efforts. The wide spectrum of potential analytes that induce a physiological response dictates that novel techniques be developed to more rapidly screen and characterize agents that are more economical and...