Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
Streptococcus pneumoniae and Influenza A Virus both primarily infect the upper respiratory tract, with more severe disease occurring during coinfection than would be caused by either pathogen independently. Until recently, characterization of the interactions between these two pathogens has occurred exclusively in the context of a host or using host-derived...
Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
The development of a market for currently non-merchantable forest material, such as harvest residues of tops and limbs of trees or small diameter trees, has been suggested as a possible win-win solution that could: (i) provide a financial incentive to help motivate treatments to reduce wildfire risk or restore forest...
Two striking characteristics of human beings are the diversity of resources that we use to sustain our lives and the extent to which we engage in coordinated, collective efforts to obtain and consume these resources. Together, these two characteristics are the foundation of human subsistence patterns. In many remote Alaskan...
Bruno Latour’s Facing Gaia provokes us to embrace our Earthboundedness to approach the problematic political ecologies of the Anthropocene. Latour’s call for the Earthbound is to re-trace networks of society, institutions, and meaning and to challenge, as enemy, those that would continue to behave as if we lived on more...
The fungus Cochliobolus victoriae causes Victoria blight of oats and Arabidopsis and is pathogenic due to its production of a compound called victorin, which induces programmed cell death in sensitive plants. Victorin sensitivity in Arabidopsis is conferred by the dominant gene LOCUS ORCHESTRATING VICTORIN EFFECTS1 (LOV1), which encodes a coiled-coil-nucleotide...
Wheat (Triticum aestivum) is a highly valuable crop that makes up a large portion of the world’s food. However, breeding for improved varieties with desirable characteristics can be a challenge. This research examined two different issues wheat breeders deal with throughout the selection process all the way to production of...