The 2007 Intergovernmental Panel on Climate Change assessment established that the effect of clouds on climate contributes the largest uncertainty in predicting the future climate. Satellite observations provide an opportunity for learning about the behavior of clouds. This thesis seeks to assess the accuracy of cloud properties retrieved from multispectral...
Per- and polyfluoroalkyl substances (PFAS) are a broad class of anthropogenic chemicals characterized by highly stable carbon-fluorine (C-F) bonds. PFAS are widely used in industrial and consumer products for their surface-active and stain-resistant properties and are ubiquitously detected in environmental media, biota, and human biomatrices. Although some PFAS are known...
All animals have developed the critical ability to detect, respond to, and detoxify a large array of environmental chemicals and stressors that can cause adverse health effects. Important examples of landmark contaminants around the world are polycyclic aromatic hydrocarbons (PAHs) and dioxins, both of which can act via the aryl...
The field of toxicology is challenged with a vast number of environmental chemicals and mixtures to which humans and ecosystems are exposed with limited toxicity data available. Chemical hazard assessment traditionally utilizes mammalian models and can be both cost- and time-limiting and may pose ethical concerns. To rapidly tackle this...
Per- and polyfluoroalkyl substances (PFAS) are contaminants of concern because they do not readily degrade in the environment. Some in vivo studies report that PFAS alter neurological development and are carcinogenic. Perfluorohexanesulfonamide (FHxSA) and 6:2 fluorotelomer sulfonate (6:2 FTS) are two PFASs, which are often detected in drinking water sources....
Graphene and its derivatives are two-dimensional hexagonal lattices that possess desirable physicochemical properties leading to an ever-expanding list of industrial and biomedical uses. Graphene oxides (GOs) are becoming a popular graphene alternative and while there have been human safety studies, investigations of developmental toxicity are lacking. The use of distinct...
Many research projects suffer from limited data causing poor statistical analysis or limited results. The movement to high throughput methods has been building for many years and cross many different disciplines. Lots of these methods start out using pathways that generate large amounts of data but have limited methods to...
Dwell time low cycle fatigue (DLCF), low cycle fatigue (LCF), and creep tests were performed at ambient temperature on Ti-6Al-2Sn-4Zr-2Mo-0.1Si (Ti-6242Si). Test specimens were solution annealed at various temperatures below the beta transus to control the volume fraction of primary alpha. The influence of the changes in primary alpha phase...
High impact loading activities such as jumping, performed during childhood is advocated as one preventive method for increasing peak bone mass. Thus, we conducted a randomized intervention to examine the effect of high impact loading on bone mass in 34 pre-pubescent boys and girl over a seven month period. Participants...
To examine the potential for exercise to build bone mass during growth, objectives of this dissertation included: 1) determine the effects of 7 months of jumping followed by 7 months of detraining on hip and spine bone mass in the prepubertal children; 2) determine variables that best predict bone mineral...