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  • Himeradine A : synthetic efforts towards himeradine A and related natural products, a Michael reaction focused approach

    Creator:
    Collett, Nathan D.
    Abstract:
    Lycopodium alkaloids have generated enormous amounts of interest from the scientific community, both as synthetic targets and for their medicinal properties. Herein is described work towards a unifying approach to large segments of the Lycopodium family. An organocatalyzed intramolecular heteroatom Michael reaction method, for the construction of piperidine and piperizine...
    Resource Type:
    Dissertation
    Full Text:
    diverse family isolated from the club mosses of North and South America, Eurasia and Africa (Figure

  • A unified approach for the total synthesis of C₁₀-functionalyzed Lycopodium alkaloids

    Creator:
    Saha, Mrinmoy
    Abstract:
    Lycopodium alkaloids have shown widespread and noteworthy biological activity, consisting of over 250 known natural products. Moreover, their structural complexity and diversity have attracted considerable attention from numerous laboratories including our own. Recently, we have developed a unified approach that would provides access to numerous, previously unprepared C₁₀-functionalized lycopodium alkaloids....
    Resource Type:
    Dissertation
    Full Text:
    club mosses which have long been used in traditional medicines in Asia and South America for the