Hallmarks of aging include the accumulation of aberrant proteins and a lower resistance to stresses. Because the endoplasmic reticulum (ER) functions to fold proteins and possesses unique stress sensing pathways, the central hypothesis of this dissertation is that the ER is a target of cellular aging and significantly underlies these...
Silicone wristbands are easy-to-wear passive samplers that have been readily adapted into environmental health studies since first reported in 2014. Wristbands can be worn during normal daily activities and sequester a wide range of bioavailable organic chemicals. This dissertation includes a thorough review of silicone wristband technology, as well as...
This thesis explores the relationship between crime, transportation network connectivity, and engineered facilities built to increase walkability through a case study of twenty-five sites within the city of Spokane, Washington. Using data spanning between 2008 and 2010, the author developed a GIS model representing conditions of the built environment, social...
An outbreak of western spruce budworm Choristoneura
occidentalis in the Blue Mountains of eastern Oregon in
1983 was treated with helicopter applied carbaryl. Effects
of the spraying on forest ants were determined from pre- and
postspray samples taken from two carbaryl sprayed and
two unsprayed plots. In each 0.75-ha plot,...
Increasing interest in hydrogen as a clean and efficient energy carrier has driven the need to improve its production and distribution methods. Of particular interest is the natural gas reforming process which currently accounts for 48% of hydrogen production in the United States. Existing natural gas delivery infrastructure and challenges...
Currently, the only anthrax vaccine licensed for human use in the United States is the Anthrax-vaccine-absorbed (AVA or Biothrax®). AVA suffers from several drawbacks, including a complicated and lengthy dosing schedule that requires six initial injections administered over eighteen months, followed by annual boosters. Therefore, a new generation anthrax vaccine...
The neurohypophysial peptide system is involved in modulating a
variety of physiological, neurological, and behavioral responses in
vertebrates. The principal forms of these peptides in non-mammalian
tetrapods are vasotocin (VT) and mesotocin (MT). The studies described
in this thesis used pharmacological, molecular, and biochemical
techniques, along with phylogenetic analyses, to...
The Wadi el Far'a catchment is a tributary of the Jordan River located entirely the West Bank in the Middle East. Increasing population in the catchment, with economic development, is likely to increase water needs in this water region. In the water management of the region, agriculture is an essential...
The last two decades have seen many new continuum models for
electromagnetic materials which were constructed by merely adding
terms to the classical balance laws and constitutive equations. Nonlocal
theories, such as the one developed by A. C. Eringen., however,
depart from the traditional approaches by accounting for the effects...