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- Creator:
- Dong, Wei, Stockwell, Virginia O., and Goyer, Aymeric
- Abstract:
- Thiamin is an essential nutrient in the human diet. Severe thiamin deficiency leads to beriberi, a lethal disease which is common in developing countries. Thiamin biofortification of staple food crops is a possible strategy to alleviate thiamin deficiency-related diseases. In plants, thiamin plays a role in the response to abiotic...
- Resource Type:
- Article
- Full Text:
- Metabolic Engineering Running head Thiamin engineering in plants Authors: Wei Dong1,2,3
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- Creator:
- Dong, Wei, Thomas, Nicholas, Ronald, Pamela C., and Goyer, Aymeric
- Abstract:
- Thiamin diphosphate (ThDP), also known as vitamin B1, serves as an enzymatic cofactor in glucose metabolism, the Krebs cycle, and branched-chain amino acid biosynthesis in all living organisms. Unlike plants and microorganisms, humans are not able to synthesize ThDP de novo and must obtain it from their diet. Staple crops...
- Resource Type:
- Article
- Full Text:
- , Germany *Correspondence: Aymeric Goyer aymeric.goyer@oregonstate.edu †Present address: Wei Dong
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- Creator:
- Dong, Wei, Thomas, Nicholas, Ronald, Pamela C., and Goyer, Aymeric
- Abstract:
- Thiamin diphosphate (ThDP), also known as vitamin B1, serves as an enzymatic cofactor in glucose metabolism, the Krebs cycle, and branched-chain amino acid biosynthesis in all living organisms. Unlike plants and microorganisms, humans are not able to synthesize ThDP de novo and must obtain it from their diet. Staple crops...
-
- Creator:
- Dong, Wei, Thomas, Nicholas, Ronald, Pamela C., and Goyer, Aymeric
- Abstract:
- Thiamin diphosphate (ThDP), also known as vitamin B1, serves as an enzymatic cofactor in glucose metabolism, the Krebs cycle, and branched-chain amino acid biosynthesis in all living organisms. Unlike plants and microorganisms, humans are not able to synthesize ThDP de novo and must obtain it from their diet. Staple crops...
- Full Text:
- , Germany *Correspondence: Aymeric Goyer aymeric.goyer@oregonstate.edu †Present address: Wei Dong
-
- Creator:
- Dong, Wei, Thomas, Nicholas, Ronald, Pamela C., and Goyer, Aymeric
- Abstract:
- Thiamin diphosphate (ThDP), also known as vitamin B1, serves as an enzymatic cofactor in glucose metabolism, the Krebs cycle, and branched-chain amino acid biosynthesis in all living organisms. Unlike plants and microorganisms, humans are not able to synthesize ThDP de novo and must obtain it from their diet. Staple crops...
- Resource Type:
- Article
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- Creator:
- Zeng, Yi, Nie, Chao, Min, Junxia, Liu, Xiaomin, Li, Mengmeng, Chen, Huashuai, Xu, Hanshi, Wang, Mingbang, Ni, Ting, Li, Yang, Yan, Han, Zhang, Jin-Pei, Song, Chun, Chi, Li-Qing, Wang, Han-Ming, Dong, Jie, Zheng, Gu-Yan, Lin, Li, Qian, Feng, Qi, Yanwei, Liu, Xiao, Cao, Hongzhi, Wang, Yinghao, Zhang, Lijuan, Li, Zhaochun, Zhou, Yufeng, Wang, Yan, Lu, Jiehua, Li, Jianxin, Qi, Ming, Bolund, Lars, Yashin, Anatoliy, Land, Kenneth C., Gregory, Simon, Yang, Ze, Gottschalk, William, Tao, Wei, Wang, Jian, Wang, Jun, Xu, Xun, Bae, Harold, Nygaard, Marianne, Christiansen, Lene, Christensen, Kaare, Franceschi, Claudio, Lutz, Michael W., Gu, Jun, Tan, Qihua, Perls, Thomas, Sebastiani, Paola, Deelen, Joris, Slagboom, Eline, Hauser, Elizabeth, Xu, Huji, Tian, Xiao-Li, Yang, Huanming, and Vaupel, James W.
- Abstract:
- Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
- Full Text:
- , Han-Ming Wang 8 , Jie Dong 8 , Gu-Yan Zheng 8 , Li Lin 5 , Feng Qian 5 , Yanwei Qi 3,9 , Xiao
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- Creator:
- Zeng, Yi, Nie, Chao, Min, Junxia, Liu, Xiaomin, Li, Mengmeng, Chen, Huashuai, Xu, Hanshi, Wang, Mingbang, Ni, Ting, Li, Yang, Yan, Han, Zhang, Jin-Pei, Song, Chun, Chi, Li-Qing, Wang, Han-Ming, Dong, Jie, Zheng, Gu-Yan, Lin, Li, Qian, Feng, Qi, Yanwei, Liu, Xiao, Cao, Hongzhi, Wang, Yinghao, Zhang, Lijuan, Li, Zhaochun, Zhou, Yufeng, Wang, Yan, Lu, Jiehua, Li, Jianxin, Qi, Ming, Bolund, Lars, Yashin, Anatoliy, Land, Kenneth C., Gregory, Simon, Yang, Ze, Gottschalk, William, Tao, Wei, Wang, Jian, Wang, Jun, Xu, Xun, Bae, Harold, Nygaard, Marianne, Christiansen, Lene, Christensen, Kaare, Franceschi, Claudio, Lutz, Michael W., Gu, Jun, Tan, Qihua, Perls, Thomas, Sebastiani, Paola, Deelen, Joris, Slagboom, Eline, Hauser, Elizabeth, Xu, Huji, Tian, Xiao-Li, Yang, Huanming, and Vaupel, James W.
- Abstract:
- Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
- Full Text:
- Gottschalk15, Wei Tao16, Jian Wang3,17, Jun Wang3,18, Xun Xu3, Harold Bae19, Marianne Nygaard20, Lene
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- Creator:
- Zeng, Yi, Nie, Chao, Min, Junxia, Liu, Xiaomin, Li, Mengmeng, Chen, Huashuai, Xu, Hanshi, Wang, Mingbang, Ni, Ting, Li, Yang, Yan, Han, Zhang, Jin-Pei, Song, Chun, Chi, Li-Qing, Wang, Han-Ming, Dong, Jie, Zheng, Gu-Yan, Lin, Li, Qian, Feng, Qi, Yanwei, Liu, Xiao, Cao, Hongzhi, Wang, Yinghao, Zhang, Lijuan, Li, Zhaochun, Zhou, Yufeng, Wang, Yan, Lu, Jiehua, Li, Jianxin, Qi, Ming, Bolund, Lars, Yashin, Anatoliy, Land, Kenneth C., Gregory, Simon, Yang, Ze, Gottschalk, William, Tao, Wei, Wang, Jian, Wang, Jun, Xu, Xun, Bae, Harold, Nygaard, Marianne, Christiansen, Lene, Christensen, Kaare, Franceschi, Claudio, Lutz, Michael W., Gu, Jun, Tan, Qihua, Perls, Thomas, Sebastiani, Paola, Deelen, Joris, Slagboom, Eline, Hauser, Elizabeth, Xu, Huji, Tian, Xiao-Li, Yang, Huanming, and Vaupel, James W.
- Abstract:
- Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health and longevity. Here we report a genome-wide association study (GWAS) of Han Chinese with a sample size 2.7 times the...
- Resource Type:
- Article
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- Creator:
- Dickey, T., Banner, M. L., Bhandari, P., Boyd, Timothy John, 1958-2013, Carvalho, L., Chang, G., Chao, Y., Czerski, H., Darecki, M., Dong, C., Farmer, D., Freeman, S., Gemmrich, J., Gernez, P., Hall-Patch, N., Holt, B., Jiang, S., Jones, C., Kattawar, G., LeBel, D., Lenain, L., Lewis, M., Liu, Y., Logan, L., Manov, D., Melville, W. K., Moline, M. A., Morison, R., Nencioli, F., Pegau, W. S., Reineman, B., Robbins, I., Roettgers, R., Schultz, H., Shen, L., Shinki, M., Slivkoff, M., Sokolski, M., Spada, F., Statom, N., Stramski, D., Sutherland, P., Twardowski, M., Vagle, S., Van Dommelen, R., Voss, K., Washburn, L., Wei, J., Wijesekera, H., Wurl, O., Yang, D., Yildiz, S., You, Y., Yue, D. K. P., Zaneveld, R., and Zappa, C. J.
- Abstract:
- Optical variability occurs in the near-surface and upper ocean on very short time and space scales (e.g., milliseconds and millimeters and less) as well as greater scales. This variability is caused by solar, meteorological, and other physical forcing as well as biological and chemical processes that affect optical properties and...
- Resource Type:
- Article
- Full Text:
- . Dong,12 D. Farmer,13 S. Freeman,14 J. Gemmrich,15 P. Gernez,16 N. Hall-Patch,17 B. Holt,18 S. Jiang,1