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- Creator:
- Lee, Seung-Tae, Muench, Marcus O., Fomin, Marina E., Houseman, E. Andres, and et al.
- Abstract:
- We investigated DNA methylomes of pediatric B-cell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and high-definition microarrays, along with RNA expression profiles. Epigenetic alteration of B-ALLs occurred in two tracks: de novo methylation of small functional compartments and demethylation of large intercompartmental backbones. The deviations were exaggerated in lamina-associated...
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- Creator:
- Lee, Seung-Tae, Muench, Marcus O., Fomin, Marina E., Houseman, E. Andres, and et al.
- Abstract:
- We investigated DNA methylomes of pediatric B-cell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and high-definition microarrays, along with RNA expression profiles. Epigenetic alteration of B-ALLs occurred in two tracks: de novo methylation of small functional compartments and demethylation of large intercompartmental backbones. The deviations were exaggerated in lamina-associated...
- Full Text:
- Lee, S. T., Muench, M. O., Fomin, M. E., Xiao, J., Zhou, M., de Smith, A., ... & Wiemels, J. L. (2015
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- Creator:
- Lee, Seung-Tae, Muench, Marcus O., Fomin, Marina E., Xiao, Jianqiao, Zhou, Mi, de Smith, Adam, Martín-Subero, José I., Heath, Simon, Houseman, E. Andres, Roy, Ritu, Wrensch, Margaret, Wiencke, John, Metayer, Catherine, and Wiemels, Joseph L.
- Abstract:
- We investigated DNA methylomes of pediatric B-cell acute lymphoblastic leukemias (B-ALLs) using whole-genome bisulfite sequencing and high-definition microarrays, along with RNA expression profiles. Epigenetic alteration of B-ALLs occurred in two tracks: de novo methylation of small functional compartments and demethylation of large intercompartmental backbones. The deviations were exaggerated in lamina-associated...
- Resource Type:
- Article
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- Creator:
- Traeger, Stefanie, Altegoer, Florian, Freitag, Michael, Gabaldon, Toni, Kempken, Frank, Kumar, Abhishek, Marcet-Houben, Marina, Poggeler, Stefanie, Stajich, Jason E., and Nowrousian, Minou
- Abstract:
- Fungi are a large group of eukaryotes found in nearly all ecosystems. More than 250 fungal genomes have already been sequenced, greatly improving our understanding of fungal evolution, physiology, and development. However, for the Pezizomycetes, an early-diverging lineage of filamentous ascomycetes, there is so far only one genome available, namely...
- Resource Type:
- Article
- Full Text:
- , Michael Freitag2, Toni Gabaldon3,4, Frank Kempken5, Abhishek Kumar5, Marina Marcet-Houben3,4, Stefanie
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- Creator:
- Laurance, William F., Useche, D. Carolina, Rendeiro, Julio, Kalka, Margareta, Bradshaw, Corey J. A., Sloan, Sean P., Laurance, Susan G., Campbell, Mason, Abernethy, Kate, Alvarez, Patricia, Arroyo-Rodriguez, Victor, Ashton, Peter, Benitez-Malvido, Julieta, Blom, Allard, Bobo, Kadiri S., Cannon, Charles H., Cao, Min, Carroll, Richard, Chapman, Colin, Coates, Rosamond, Cords, Marina, Danielsen, Finn, De Dijn, Bart, Dinerstein, Eric, Donnelly, Maureen A., Edwards, David, Edwards, Felicity, Farwig, Nina, Fashing, Peter, Forget, Pierre-Michel, Foster, Mercedes, Gale, George, Harris, David, Harrison, Rhett, Hart, John, Karpanty, Sarah, Kress, W. John, Krishnaswamy, Jagdish, Logsdon, Willis, Lovett, Jon, Magnusson, William, Maisels, Fiona, Marshall, Andrew R., McClearn, Deedra, Mudappa, Divya, Nielsen, Martin R., Pearson, Richard, Pitman, Nigel, van der Ploeg, Jan, Plumptre, Andrew, Poulsen, John, Quesada, Mauricio, Rainey, Hugo, Robinson, Douglas, Roetgers, Christiane, Rovero, Francesco, Scatena, Frederick, Schulze, Christian, Sheil, Douglas, Struhsaker, Thomas, Terborgh, John, Thomas, Duncan, Timm, Robert, Urbina-Cardona, J. Nicolas, Vasudevan, Karthikeyan, Wright, S. Joseph, Arias-G, Juan Carlos, Arroyo, Luzmila, Ashton, Mark, Auzel, Philippe, Babaasa, Dennis, Babweteera, Fred, Baker, Patrick, Banki, Olaf, Bass, Margot, Bila-Isia, Inogwabini, Blake, Stephen, Brockelman, Warren, Brokaw, Nicholas, Bruehl, Carsten A., Bunyavejchewin, Sarayudh, Chao, Jung-Tai, Chave, Jerome, Chellam, Ravi, Clark, Connie J., Clavijo, Jose, Congdon, Robert, Corlett, Richard, Dattaraja, H. S., Dave, Chittaranjan, Davies, Glyn, Beisiegel, Beatriz de Mello, da Silva, Rosa de Nazarepaes, Di Fiore, Anthony, Diesmos, Arvin, Dirzo, Rodolfo, Doran-Sheehy, Diane, Eaton, Mitchell, Emmons, Louise, Estrada, Alejandro, Ewango, Corneille, Fedigan, Linda, Feer, Francois, Fruth, Barbara, Willis, Jacalyn Giacalone, Goodale, Uromi, Goodman, Steven, Guix, Juan C., Guthiga, Paul, Haber, William, Hamer, Keith, Herbinger, Ilka, Hill, Jane, Huang, Zhongliang, Sun, I. Fang, Ickes, Kalan, Itoh, Akira, Ivanauskas, Natalia, Jackes, Betsy, Janovec, John, Janzen, Daniel, Jiangming, Mo, Jin, Chen, Jones, Trevor, Justiniano, Hermes, Kalko, Elisabeth, Kasangaki, Aventino, Killeen, Timothy, King, Hen-biau, Klop, Erik, Knott, Cheryl, Kone, Inza, Kudavidanage, Enoka, Ribeiro, Jose Lahoz da Silva, Lattke, John, Laval, Richard, Lawton, Robert, Leal, Miguel, Leighton, Mark, Lentino, Miguel, Leonel, Cristiane, Lindsell, Jeremy, Ling-Ling, Lee, Linsenmair, K. Eduard, Losos, Elizabeth, Lugo, Ariel, Lwanga, Jeremiah, Mack, Andrew L., Martins, Marlucia, McGraw, W. Scott, McNab, Roan, Montag, Luciano, Thompson, Jo Myers, Nabe-Nielsen, Jacob, Nakagawa, Michiko, Nepal, Sanjay, Norconk, Marilyn, Novotny, Vojtech, O'Donnell, Sean, Opiang, Muse, Ouboter, Paul, Parker, Kenneth, Parthasarathy, N., Pisciotta, Katia, Prawiradilaga, Dewi, Pringle, Catherine, Rajathurai, Subaraj, Reichard, Ulrich, Reinartz, Gay, Renton, Katherine, Reynolds, Glen, Reynolds, Vernon, Riley, Erin, Roedel, Mark-Oliver, Rothman, Jessica, Round, Philip, Sakai, Shoko, Sanaiotti, Tania, Savini, Tommaso, Schaab, Gertrud, Seidensticker, John, Siaka, Alhaji, Silman, Miles R., Smith, Thomas B., de Almeida, Samuel Soares, Sodhi, Navjot, Stanford, Craig, Stewart, Kristine, Stokes, Emma, Stoner, Kathryn E., Sukumar, Raman, Surbeck, Martin, Tobler, Mathias, Tscharntke, Teja, Turkalo, Andrea, Umapathy, Govindaswamy, van Weerd, Merlijn, Rivera, Jorge Vega, Venkataraman, Meena, Venn, Linda, Verea, Carlos, de Castilho, Carolina Volkmer, Waltert, Matthias, Wang, Benjamin, Watts, David, Weber, William, West, Paige, Whitacre, David, Whitney, Ken, Wilkie, David, Williams, Stephen, Wright, Debra D., Wright, Patricia, Xiankai, Lu, Yonzon, Pralad, and Zamzani, Franky
- Abstract:
- The rapid disruption of tropical forests probably imperils global biodiversity more than any other contemporary phenomenon¹⁻³. With deforestation advancing quickly, protected areas are increasingly becoming final refuges for threatened species and natural ecosystem processes. However, many protected areas in the tropics are themselves vulnerable to human encroachment and other environmental...
- Resource Type:
- Article
- Full Text:
- Light-loving butterflies Human diseases 2 9 0 | N A T U R E | V O L 4 8 9 | 1 3 S E P T E M B E R 2 0 1