The objective of this thesis is to show that by separating the two major anthropogenic changes caused in riverine input to the north shore of the Black Sea, it is possible to describe distinct linkages between ongoing ecological changes in the Black Sea, and 1) flow reduction, and 2) nutrient...
Coast redwood (Sequoia sempervirens) (D. Don) Endl. is a host for Phytophthora ramorum but it was unclear if the pathogen represents a significant disease risk to this tree species. In this study the susceptibility of coast redwood seedlings and the likelihood of sporulation on redwood were examined. Two methods were...
Because arginine vasotocin (AVT) activates male sexual behaviors in the rough-skinned newt (Taricha granulosa), quantitative autoradiography with radiolabelled arginine vasopressin (³H-AVP) was used to localize and characterize putative AVT receptors in the brain of this amphibian. Binding of ³H-AVP to sites within the medial pallium was saturable, specific, reversible, of...
The opportunistic pathogen Pseudomonas aeruginosa possesses two LuxR-LuxI
type quorum-sensing systems that use diffusible acyl-homoserine lactone molecules to
autoinduce and coordinate expression of multiple virulence factors. We conducted a highthroughput
screen for mutants deficient in skim-milk proteolysis—a quorum-sensing
dependent phenotype—using a nonredundant transposon-insertion library representing
most nonessential genes in P....
This dissertation presents a research series demonstrating the use of pharmacokinetic modeling and simulations as tools to assess drug concentration and disposition in patient populations. For drugs requiring therapeutic drug monitoring, these tools are necessary to ensure patients are receiving a safe and effective dose of medication to address their...
Decreases in pavement program funding levels have encouraged paving agencies to adopt higher levels of recycled materials into their asphalt mixes. In order to fully evaluate the effects of recycled asphalt pavement (RAP) in Hot Mix Asphalt (HMA) mixes, the level of blending between the RAP and virgin binders in...
To quantify the reproductive behavior of male and female gray-tailed
voles, Microtus canicaudus, under conditions of natural
estrus, sexually experienced pairs were observed in a standardized
behavior test for 10 hours. The total duration of sexual
interactions averaged 223 minutes, which is considerably longer than
previously published reports on microtines....
The vegetative communities in the subalpine meadows of Hunts
Cove, Mt. Jefferson, and some of the major environmental factors
affecting them were studied in the summer of 1971. Hunts Cove is in
the subalpine Tsuga mertensiana parkland of the Central Oregon High
Cascades. Habitats within the Cove vary considerably; elevation...
