Genomic instability drives tumorigenesis, but how it is initiated in sporadic neoplasias is unknown. In early preneoplasias, alterations at chromosome fragile sites arise due to DNA replication stress. A frequent, perhaps earliest, genetic alteration in preneoplasias is deletion within the fragile FRA3B/FHIT locus, leading to loss of Fhit protein expression....
This paper presents a new Rock Share Estimation (RSE) procedure that can estimate the cost
of forest road construction. One of the key elements of the total cost in road construction is the
cost of embankment. The proportion of the rock directly influences the price of this activity.
Hence, a...
In the second chapter, a foam-core meniscus coating process was developed for retrofitting 100 nm-scale sol-gel anti-reflective coatings onto in-field solar panels through the deposition, evaporation, and curing of wet films.Advantages of this technique include the means to control fluid flow relative to substrate motion and the ability to conform...
Emergence of highly accurate Convolutional Neural Networks (CNNs) with the capability to process large datasets, has led to their popularity in many applications, including safety/security-sensitive (e.g. disease recognition, self-driving cars). Despite the high accuracy of convolutional neural networks, they have been found to be susceptible to adversarial noise added to...
Scour is the main cause of bridge failures in the United States. Bridge failures raise a hazard to the safety of the traveling public as well as the massive economic consequences due to the high cost of constructing a new or a replacement bridge. The Oregon Department of Transportation (ODOT)...
Accurate information of power network parameters is essential for performing various power system monitoring and control tasks including state estimation, economic dispatch, and contingency analysis. In this paper, we present a novel approach of power network parameter correction wherein we exploit the sparse nature of parameter errors. Parameter error correction...
Since the introduction of lean manufacturing by Toyota and publication by Womack and Jones, organizations have realized sizeable gains through lean process improvement. The spread of lean practices across organizations and industries – from manufacturing to healthcare and construction – requires adjustments of the lean process and, in the case...
Treatment of extrahepatic portosystemic shunts provides many options, including cellophane banding. These cellophane bands are secured with a ligation clip. Weck® offers two forms of these: the stainless steel Hemoclip, and the polymer Hem-o-lok. This in vitro study compares the mechanical strength of these two of types of clips by...
Weight-loss supplements typically fall into 1 of 4 categories depending on their hypothesized mechanism of action: products that block the absorption of fat or carbohydrate, stimulants that increase thermogenesis, products that change metabolism and improve body composition, and products that suppress appetite or give a sense of fullness. Each category...
Despite increased understanding of the benefits of wetlands, global wetland area continues to decrease. Wetlands are being lost at an alarming rate, and with them, biodiversity, floodwater storage, water purification, and countless other functions. There is little information available about mechanisms to manage transboundary wetlands. While the Ramsar Convention is...