Farensoid X Receptor (FXR) is a very flavoring protein for the treatment and prevention of the many conditions related to metabolic syndrome. Our experiment explores the binding activities of FXR when introduced to various natural and synthetic ligands. Currently, an initial assay showing the Stern-Volmer relationship of our date supports...
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. Kevin Ahern
Liping Yang
Stefan Lucchini
The HowardHughesMedicalInstitute
Undergraduate
The toxicity of a group of oxygenated polycyclic aromatic hydrocarbons (OPAHs) was investigated using embryonic zebrafish. An immediate goal was to determine the relative toxicity of these compounds and to explore the toxicity mechanisms. It is thought that some OPAHs cause toxicity by binding and activating the aryl hydrocarbon receptor...
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HughesMedicalInstitute
URISC
Oregon State University Honors College
CRIPPS
Dr. Robert Tanguay and Lab
We proposed to test the hypothesis that ecologically relevant concentrations of pesticide mixtures will increase susceptibility of metamorphic amphibians to a fungal pathogen known as Batrachochytrium dendrobatidis, or Bd. Bd has received considerable attention as one of the causes of declining amphibian populations. We hypothesized that exposure to the contaminants...
Farensoid X Receptor (FXR) is a very flavoring protein for the treatment and prevention of the many conditions related to metabolic syndrome. Our experiment explores the binding activities of FXR when introduced to various natural and synthetic ligands. Currently, an initial assay showing the Stern-Volmer relationship of our date supports...
Full Text:
Stefan Lucchini
The HowardHughesMedicalInstitute
Undergraduate Research, Innovation, Scholarship
We proposed to test the hypothesis that ecologically relevant concentrations of pesticide mixtures will increase susceptibility of metamorphic amphibians to a fungal pathogen known as Batrachochytrium dendrobatidis, or Bd. Bd has received considerable attention as one of the causes of declining amphibian populations. We hypothesized that exposure to the contaminants...
In this study, the gene expression levels between 6 month old mice and 26 month
old mice were compared. The purpose of this research was to identify genes that are
differentially regulated due to aging. The results showed 148 significantly differentiated
genes in the analysis of a total of 44,170...
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Gombart
lab
Dr.
Kevin
Ahern
HowardHughesMedicalInstitute
(HHMI
Parathyroid hormone (PTH) is directly involved in breast cancer (BC) metastasis, as well as the severity of metastatic tumors. Excess PTH, caused by insufficient dietary calcium, may be an important and preventable factor affecting BC metastasis to bone. PTH levels increase with age in most women, largely due to insufficient...
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PowerPoint Presentation
HHMI Undergraduate Research
Parathyroid hormone (PTH) is directly involved in breast cancer (BC) metastasis, as well as the severity of metastatic tumors. Excess PTH, caused by insufficient dietary calcium, may be an important and preventable factor affecting BC metastasis to bone. PTH levels increase with age in most women, largely due to insufficient...
Full Text:
PowerPoint Presentation
HHMI Undergraduate
Research Project