Automatic music transcription (AMT) is the task, given an acoustic representation of music, to recover a symbolic notation of the written notes expressed by the sound. Transcribing music with multiple notes sounding simultaneously is difficult for both humans and machines. Much existing work on AMT has focused on suitable acoustic...
Most tasks in natural language processing (NLP) involves structured information from both input (e.g., a sentence or a paragraph) and output (e.g., a tag sequence, a parse tree or a translated sentence). While neural models achieve great successes in other domains such as computer vision, applying those frameworks to NLP...
Machine learning models for natural language processing have traditionally relied on large numbers of discrete features, built up from atomic categories such as word forms and part-of-speech labels, which are considered completely distinct from each other. Recently however, the advent of dense feature representations coupled with deep learning techniques has...
Cell migration is fundamental for physiological processes such as immune re-sponses, wound healing and development. It is also a critical characteristic of metastatic cancer cells. An extensive amount of studies have focused on 2D sub-strates in order to understand the mechanism of cancer metastasis. However, much less is known about...
Cancer cell migration in three-dimensional extracellular matrix is a major cause of death for cancer patients. Although extensive studies have elucidated detailed mechanism of single cell 3D invasion and cell-ECM interaction, 3D collective cancer invasion is still poorly understood. 3D collective migration models have unveiled unexpected degrees of diversity and...
Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
At the intersection of basic science research and clinical relevance, cancer metastasis and cell invasion is a multifaceted problem that has been investigated for the past several decades. Importantly, cancer cell plasticity, the ability of a single cell to change its phenotype without genetic mutations in response to environmental cues,...
The ability for individual cells and multicellular networks to process information contained in perceived stimuli is of vital importance to their proper functioning and ultimately their cellular fate. The primary mechanism employed by cells to this end is the use of biochemical signaling in which a series of molecular events...
The structure and mechanics of tissues affect many important cellular functions such as migration, differentiation, and growth. Mechanical interactions between cells and the extracellular matrix (ECM), as well as ECM-mediated mechanical communication between cells, plays a part in coordinating collective cellular dy- namics during critical processes such as morphogenesis, tissue...
Direct sequence spread spectrum (DSSS) was initially used for anti-jamming in military applications and was later developed in other commercial applications. Walsh codes, which are a set of mutually orthogonal codes, are one type of the spreading codes used in DSSS systems. For any spreading codes of length N, these...