Index Catalog // ScholarsArchive@OSU

Alternative Exon 3 Inclusion in the Vitamin D Receptor (VDR) Modulates Transcriptional Activity for Target Genes in a Ligand-Independent Manner

Creator:: Cameron, Alex N., Annalora, Andrew, and Marcus, Craig
Abstract:: Xenobiotic exposures may induce alternative splicing in the pre-mRNA of nuclear hormone receptor (NHR) genes, yielding unpredictable patterns of gene expression that may promote adverse drug events and promote environmental disease. Informed by observations in the androgen receptor (AR; class I NHR), whereby alternatively-spliced AR transcripts induce ligand-independent hormone signaling...
Resource Type:: Poster
Full Text:: Manner. Alex N. Cameron, Andrew Annalora, Craig Marcus and Patrick Iversen. Department of

Role of Melanocytic Vitamin D Receptor (VDR) in UVB-induced Melanocyte Homeostasisand Keratinocytic Retinoid–X-Receptor α (RXRα) in UVB Induced Melanomagenesis

Creator:: Chagani, Sharmeen
Abstract:: Cutaneous melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment-producing melanocytes, with a diagnosis of metastasis indicating a median survival rate of less than a year. Solar ultraviolet (UV) radiation, especially childhood sun exposure, is an important etiological risk factor of melanoma. This DNA damage...
Resource Type:: Dissertation
Full Text:: program Dean of the Graduate School I understand that my

Rutledge Patrick - Research Thesis Final (June 11 2013) .pdf

Creator:: Rutledge, Patrick
Abstract:: To initiate the defense response to an invading pathogen, plants utilize an array of immune receptors to recognize virulence effectors. Virulence effectors are released by pathogens to suppress immune responses in target hosts. These effectors are recognized by a family of resistance proteins known as nucleotide-binding leucine-rich repeat (NB-LRR) proteins....
Full Text:: © Copyright by Patrick Rutledge, June 5, 2013 All rights reserved I understand that my

IversenPatrickEnvirMoleToxAVI-7288MarburgVirus.pdf

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: ., Patrick L. Iversen, Ph.D., Travis K. Warren, Ph.D., Jay B. Saoud, Ph.D., Mohamed Al-Ibrahim, M.B., Ch.B

IversenPatrickEnvirMoleToxAVI-7288MarburgVirusSlideSet.pptx

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: Nonhuman Primates and Humans Alison E. Heald, M.D., Jay S. Charleston, Ph.D., Patrick L. Iversen, Ph.D

IversenPatrickEnvirMoleToxAVI-7288MarburgVirusSupplementaryProtocol.pdf

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: , Iversen PL, et al. AVI-7288 for Marburg virus in nonhuman primates and humans. N Engl J Med 2015;373:339

IversenPatrickEnvirMoleToxAVI-7288MarburgVirusSupplementaryDisclosures.pdf

Creator:: Heald, Alison E., Charleston, Jay S., Iversen, Patrick L., and et al.
Abstract:: BACKGROUND: AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined. METHODS: We assessed the efficacy of AVI-7288 in a series of studies involving a lethal challenge with MARV in nonhuman primates. The...
Full Text:: Information Section 1. 1. Given Name (First Name) Patrick 2. Surname (Last Name) Iversen 4. Are you the

Inhibition of Hepatitis E Virus Replication by Peptide-Conjugated Morpholino Oligomers

Creator:: Nan, Yuchen, Ma, Zexu, Kannan, Harilakshmi, Stein, David A., Iversen, Patrick I., Meng, Xiang-Jin, and Zhang, Yan-Jin
Abstract:: Hepatitis E virus (HEV) infection is a cause of hepatitis in humans worldwide. Recently, persistent and chronic HEV infections have been recognized as a serious clinical problem, especially in immunocompromised individuals. To date, there are no FDA-approved HEV-specific antiviral drugs. In this study, we designed and evaluated antisense peptide-conjugated morpholino...
Resource Type:: Article
Full Text:: Peptide-Conjugated Morpholino Oligomers Nan, Y., Ma, Z., Kannan, H., Stein, D. A., Iversen, P. I., Meng

Internationalization Processes in the Salmon Farming Industry

Creator:: Iversen, Audun
Abstract:: In this paper the focus is on the process of internationalization and globalization in the seafood farming industry. The development in the five largest and international farming firms is studied in relation to both traditional stage-theories of internationalization, and more recent theories, like the RBV, contributing to IB. Integration processes,...
Resource Type:: Research Paper
Full Text:: Japan Proceedings INTERNATIONALIZATION PROCESSES IN THE SALMON FARMING INDUSTRY Audun Iversen

Globalization and strategies in the Norwegian fish-processing industry - coping or proactive restructuring?

Creator:: Iversen, Audun
Abstract:: Globalization may affect companies in the fish-processing industry in many ways. For some, globalization poses new threats, for others it represents new opportunities. Some companies see their benefit of being located close to the resources vanish, as resources are brought out of the region, processed in low-wage countries, and distributed...
Resource Type:: Research Paper
Full Text:: - processing industry – coping or proactive restructuring? Audun Iversen, Norwegian Institute of Fisheries and

ScholarsArchive@OSU

Alternative Exon 3 Inclusion in the Vitamin D Receptor (VDR) Modulates Transcriptional Activity for Target Genes in a Ligand-Independent Manner

Role of Melanocytic Vitamin D Receptor (VDR) in UVB-induced Melanocyte Homeostasisand Keratinocytic Retinoid–X-Receptor α (RXRα) in UVB Induced Melanomagenesis

Rutledge Patrick - Research Thesis Final (June 11 2013) .pdf

IversenPatrickEnvirMoleToxAVI-7288MarburgVirus.pdf

IversenPatrickEnvirMoleToxAVI-7288MarburgVirusSlideSet.pptx

IversenPatrickEnvirMoleToxAVI-7288MarburgVirusSupplementaryProtocol.pdf

IversenPatrickEnvirMoleToxAVI-7288MarburgVirusSupplementaryDisclosures.pdf

Inhibition of Hepatitis E Virus Replication by Peptide-Conjugated Morpholino Oligomers

Internationalization Processes in the Salmon Farming Industry

Globalization and strategies in the Norwegian fish-processing industry - coping or proactive restructuring?

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Conference Name

Conference Section/Track

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Funding Body

Language

License

Location

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search